Evidence map›Paper›PMID 28781577›Full record

ArticleEuropean journal of organic chemistry2016

Expeditious Synthesis of Isoquinolones and Isocoumarins with a Vinyl Borane as an Acetylene Equivalent.

Momar Toure, Saul Jaime-Figueroa, George M Burslem, Craig M Crews

Abstract read
In one paragraph

Article in European journal of organic chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Several major herb pairs containingFrontiers in pharmacology · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Momar ToureDepartments of Chemistry; Molecular, Cellular & Developmental Biology; Pharmacology, Yale University, New Haven, Connecticut 06511, United States.
Saul Jaime-FigueroaDepartments of Chemistry; Molecular, Cellular & Developmental Biology; Pharmacology, Yale University, New Haven, Connecticut 06511, United States.
George M BurslemDepartments of Chemistry; Molecular, Cellular & Developmental Biology; Pharmacology, Yale University, New Haven, Connecticut 06511, United States.
Craig M CrewsDepartments of Chemistry; Molecular, Cellular & Developmental Biology; Pharmacology, Yale University, New Haven, Connecticut 06511, United States.

Funding

Inducing Proximity: An Emerging Paradigm for New Therapeutic ModalitiesR35CA197589 · NCI · YALE UNIVERSITY · PI CRAIG M CREWS · 2015 to 2026
$10.7M
A MULTIPRONGED, PROTEIN DEGRADATION-BASED APPROACH TO INHIBIT HIV TRANSMISSIONR01AI084140 · NIAID · YALE UNIVERSITY · PI CREWS, CRAIG M · 2009 to 2012
$1.8M
NCI NIH HHS R35 CA197589NIAID NIH HHS R01 AI084140
6 · The paper itself

Abstract

An innovative and simple expeditious synthesis of 3,4-unsubstituted isoquinolones and isocoumarins starting from safe and easy to handle two-carbon acetylene equivalent was developed. The synthetic potential of this new method was further demonstrated in the facile total synthesis of two naturally occurring alkaloids:

Indexed as

boronateisocoumarinisoquinoloneSuzuki couplingvinyl ether

Identifiers

PMID28781577
PMCPMC5542060

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.