ArticleJournal of natural science, biology, and medicine
Villous Chorion: A Potential Source for Pluripotent-like Stromal Cells.
Article in Journal of natural science, biology, and medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Importance of STAT3 signaling in preeclampsia (Review).International journal of molecular medicine · 2025Review
- Toxicity, Safety, and Efficacy Studies on Mesenchymal Stem Cells Derived fromCurrent issues in molecular biology · 2022Article
- Article
- Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.Cell & bioscience · 2021Article
- Large-Scale Expansion of Human Mesenchymal Stem Cells.Stem cells international · 2020Review
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Authors and funding
4 authors.
Funding
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Abstract
contextMultipotent stromal cells are isolated from various fetal sources and studied for their phenotypic characterization and ability to differentiate into different lineages.
aimsIn this study, we aimed to isolate mesenchymal stem or stromal cells (MSCs) from villous chorion, expand under clinical scale level, compared the potency with other source of fetal-derived MSCs and studied their differentiation capabilities to form all three germ layers. SUBJECTS AND
methodsPlacenta obtained from C-section was used to isolate villous chorion-MSCs (VC-MSCs) were expanded up to tenth passage and their characteristics were assessed by proliferation rate and phenotypic characterization using fluorescence-activated cell sorting and also expanded MSCs were analyzed for differentiated into all three germ layers by cytochemical staining.
resultsStem cell isolated from VC yielded up to 2.16 × 10
conclusionsThis result suggests that the VC-MSCs are ideal source of stem cells with similar characteristics such as other adult stem cells. Thus, VC-derived MSCs can be potential clinical source in regenerative medicine.
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