Evidence map›Paper›PMID 28781319›Full record

ReviewInternal medicine (Tokyo, Japan)2017

Successful Treatment of TAFRO Syndrome with Tocilizumab, Prednisone, and Cyclophosphamide.

Taku Kikuchi, Takayuki Shimizu, Takaaki Toyama, Ryohei Abe, Shinichiro Okamoto

Open access · diamondAbstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Stepwise Treatment for TAFRO Syndrome.Journal of medical cases · 2023
    Article
  8. Review
  9. Article
  10. International definition of iMCD-TAFRO: future perspectives.Journal of clinical and experimental hematopathology : JCEH · 2022
    Article
  11. Review
  12. Article
  13. [A case report of TAFRO syndrome].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2021
    Article
  14. Fatal case of TAFRO syndrome with unilateral adrenal hemorrhage in early-stage disease.Journal of clinical and experimental hematopathology : JCEH · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Taku KikuchiDivision of Hematology, Department of Medicine, Keio University School of Medicine, Japan.
Takayuki ShimizuDivision of Hematology, Department of Medicine, Keio University School of Medicine, Japan.
Takaaki ToyamaDivision of Hematology, Department of Medicine, Keio University School of Medicine, Japan.
Ryohei AbeDivision of Hematology, Department of Medicine, Keio University School of Medicine, Japan.
Shinichiro OkamotoDivision of Hematology, Department of Medicine, Keio University School of Medicine, Japan.
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TAFRO syndrome is a rare systemic inflammatory disease characterized by thrombocytopenia, pleural effusion, fever, renal dysfunction, reticulin fibrosis of the bone marrow, and organomegaly. The clinical course varies significantly among patients. However, the prognosis is usually dismal in patients with severe TAFRO syndrome, and no optimal treatment has yet been established. We herein describe the first case of TAFRO syndrome, which was successfully treated with combination therapy consisting of tocilizumab, prednisone, and cyclophosphamide.

Indexed as

AgedAntibodies, Monoclonal, HumanizedBone MarrowCyclophosphamideDrug Therapy, CombinationEdemaFeverFibrosisGlucocorticoidsHumansLymphadenopathyMalePleural EffusionPrednisoneSyndromeThrombocytopeniaAntibodies, Monoclonal, HumanizedCyclophosphamideGlucocorticoidsPrednisonetocilizumabcyclophosphamideTAFRO syndrometocilizumab

Identifiers

PMID28781319
PMCPMC5596285
OpenAlexW2740804234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.