Evidence map›Paper›PMID 28780617›Full record

ArticleInternational ophthalmology2018

The association of Helicobacter pylori with choroidal and retinal nerve fiber layer thickness.

Mehmet Erol Can, Fatma Efe Kaplan, Mehmet Murat Uzel, Hasan Kiziltoprak, Mustafa Cagri Ergun, Mustafa Koc, Gülcin Simsek

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mehmet Erol CanDepartment of Ophthalmology, Kecioren Training and Research Hospital, Yasamkent Mah. 3208 Sk. Gulbeng Sitesi No: 1-49, Cankaya, Ankara, Turkey. drm.erolcan@gmail.com.ORCID http://orcid.org/0000-0002-3026-6681
Fatma Efe KaplanDepartment of Internal Medicine, Kecioren Training and Research Hospital, Ankara, Turkey.
Mehmet Murat UzelDepartment of Ophthalmology, Elmadag State Hospital, Ankara, Turkey.
Hasan KiziltoprakDepartment of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.
Mustafa Cagri ErgunDepartment of Internal Medicine, Kecioren Training and Research Hospital, Ankara, Turkey.
Mustafa KocDepartment of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.
Gülcin SimsekDepartment of Pathology, Kecioren Training and Research Hospital, Ankara, Turkey.
Ulucanlar Göz Eğitim ve Araştırma Hastanesi · TRMinistry of Health · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the effect of Helicobacter pylori (H. pylori) infection on choroidal thickness (CT) and retinal nerve fiber layer thickness (RNFLT).

methodsThe study included 25 patients with H. pylori infection and 25 healthy individuals as the control group. Helicobacter pylori patients were classified as the pre-treatment (Group 1; n: 25) and the post-treatment (Group 2; n: 25). RNFLT and CT were measured before and after treatment of H. pylori infection, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (Spectralis, Heidelberg Engineering, Heidelberg, Germany). The axial length and intraocular pressure were also measured.

resultsThe mean subfoveal CT was 320.96 ± 29.15 μm in Group 1 and 287.48 ± 49.17 in the control group (p = 0.007), while the mean subfoveal CT did not show any difference between Group 2 and the control group (p > 0.05). No statistically significant difference was determined between the H. pylori patients and the control group in respect of RNFLT values (p > 0.05).

conclusionsCT increases during H. pylori infection and returns to the normal range within 6 weeks of treatment. RNFLT does not show any change during H. pylori infection. The data related to the subfoveal CT may be useful in understanding the pathogenesis of central serous chorioretinopathy developing in H. pylori patients.

Indexed as

AdultCentral Serous ChorioretinopathyChoroidFemaleGastric MucosaHelicobacter InfectionsHelicobacter pyloriHumansMaleMiddle AgedNerve FibersOptic DiskProspective StudiesRetinal Ganglion CellsTomography, Optical CoherenceYoung AdultChoroidal thicknessEnhanced depth imaging optical coherence tomography (EDI-OCT)Helicobacter pylori eradicationHelicobacter pylori infectionRetinal nerve fiber layer thickness

Identifiers

PMID28780617
OpenAlexW2743397176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.