Evidence map›Paper›PMID 28780320›Full record

ArticleMethods (San Diego, Calif.)2017

Non-invasive intravital imaging of head and neck squamous cell carcinomas in live mice.

Panomwat Amornphimoltham, Jamie Thompson, Nicolas Melis, Roberto Weigert

Open access · greenAbstract read
In one paragraph

Article in Methods (San Diego, Calif.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Multiphoton intravital microscopy of rodents.Nature reviews. Methods primers · 2022
    Article
  10. The Indiana O'Brien Center for Advanced Renal Microscopic Analysis.American journal of physiology. Renal physiology · 2021
    Review
  11. Intravital Imaging Techniques for Biomedical and Clinical Research.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Panomwat AmornphimolthamIntracellular Membrane Trafficking Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, USA.
Jamie ThompsonIntracellular Membrane Trafficking Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, USA.
Nicolas MelisLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr. Rm 2050B, Bethesda, MD 20892, USA.
Roberto WeigertLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Dr. Rm 2050B, Bethesda, MD 20892, USA; Intracellular Membrane Trafficking Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, USA. Electronic address: weigertr@mail.nih.gov.
National Institute of Dental and Craniofacial Research · USNational Institutes of Health · US

Funding

Molecular mechanisms of membrane remodelingZIABC011682 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WEIGERT, ROBERTO · 2016 to 2025
$17.5M
Intramural NIH HHS ZIA BC011682
6 · The paper itself

Abstract

Head and neck squamous cell carcinoma is one of the most common cancers with a 50% 5-year survival rate. Understanding the mechanisms that control development, progression, and spreading of the tumor to distal sites is of paramount importance to develop effective therapies. Here, we describe a minimally invasive procedure, which enables performing intravital microscopy of the mouse tongue in models for oral cancer and provides structural and dynamic information of the tumors at cellular and subcellular level.

Indexed as

AnimalsCarcinoma, Squamous CellCell Line, TumorFemaleGene Knock-In TechniquesHead and Neck NeoplasmsHumansIntravital MicroscopyMiceMice, NudeMice, SCIDXenograft Model Antitumor Assays

Identifiers

PMID28780320
PMCPMC5600699
OpenAlexW2742779998

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.