Evidence map›Paper›PMID 28779373›Full record

ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2017

Ethical Considerations of Patient-Funded Research for Multiple Sclerosis Therapeutics.

Lilyana Amezcua, Flavia Nelson

Abstract readReview
In one paragraph

Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Retinal stem cell transplantation: Balancing safety and potential.Progress in retinal and eye research · 2020
    Review
  2. Multiple Sclerosis: Unprecedented Progress But Significant Challenges Ahead.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lilyana AmezcuaDepartment of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. lamezcua@usc.edu.ORCID http://orcid.org/0000-0003-1542-7819
Flavia NelsonDepartment of Neurology, McGovern Medical School, University of Texas, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patient-funded research has started to emerge in multiple sclerosis studies, such as low-dose naltrexone and stem-cell therapy. While these represent greater opportunities for the physician, scientist, and patient, ethical concerns concerning protocol review, conflict of interests, and protection of subjects are reviewed.

Indexed as

Patient ParticipationHumansMultiple SclerosisTranslational Research, BiomedicalEthicsMultiple sclerosisPatient-funded research

Identifiers

PMID28779373
PMCPMC5722765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.