ArticleSurgical endoscopy2018
Barrett's esophagus before and after Roux-en-Y gastric bypass for severe obesity.
Article in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- A Systematic Review and Meta-Analysis of the Effect of Roux-en-Y Gastric Bypass on Barrett's Esophagus.Obesity surgery · 2019Pooled it
- Evaluation of reflux following sleeve gastrectomy and one anastomosis gastric bypass: 1-year results from a randomized open-label controlled trial.Surgical endoscopy · 2021Trial
- Gastroesophageal reflux disease and the phantom of Barrett's esophagus after most-often-used bariatric procedures: are future investigations necessary?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025Review
- Treatment of esophageal adenocarcinoma in patients with a history of bariatric surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2024Article
- GERD-screening before bariatric surgery: the predictive value of the GERD-HRQL questionnaire score compared with preoperative EGD findings.Surgical endoscopy · 2023Article
- Barrett`s Esophagus in Bariatric Surgery: Regression or Progression?Obesity surgery · 2023Article
- Y Not Roux-en-Y?: Resolution of Barrett's Esophagus After Surgical Conversion of Gastric Sleeve in Two Patients.Digestive diseases and sciences · 2023Article
- Indications for upper gastrointestinal endoscopy before bariatric surgery: a multicenter study.Surgical endoscopy · 2023Article
- GASTROESOPHAGEAL SYMPTOMS AFTER LAPAROSCOPIC GASTRIC BYPASS: MISTAKES IN PERFORMING THE PROCEDURE?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022Article
- The impact of bariatric and metabolic surgery on cancer development.Frontiers in surgery · 2022Review
- Reflux, Barrett's Esophagus, and Esophageal Adenocarcinoma After Bariatric Surgery.Foregut (Thousand Oaks, Calif.) · 2021Article
- Barrett's Oesophagus and Bariatric/Metabolic Surgery-IFSO 2020 Position Statement.Obesity surgery · 2021Article
- Does Laparoscopic Sleeve Gastrectomy lead to Barrett's esophagus, 5-year esophagogastroduodenoscopy findings: A retrospective cohort study.Annals of medicine and surgery (2012) · 2021Article
- Pyloroplasty and the risk of Barrett's esophagus in patients with gastroparesis.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2020Article
- Why Choosing the Roux-en-Y Gastric Bypass in a Morbid Obese with a History of a Failed Nissen Fundoplication Is Not a Dogma.Obesity surgery · 2020Article
- Esophagitis evolution after sleeve gastrectomy or gastric bypass in consecutive cases.Surgical endoscopy · 2020Article
- Preoperative Upper-GI Endoscopy Prior to Bariatric Surgery: Essential or Optional?Obesity surgery · 2020Article
- Roux-en-Y Gastric Bypass as a Treatment for Barrett's Esophagus after Sleeve Gastrectomy.Obesity surgery · 2020Article
- Impact of Gastric Bypass on Erosive Esophagitis and Barret's Esophagus.Obesity surgery · 2020Article
- FAILURE AFTER FUNDOPLICATION: RE-FUNDOPLICATION? IS THERE A ROOM FOR GASTRECTOMY? IN WHICH CLINICAL SCENARIES?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2019Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBarrett's esophagus (BE) has been associated with obesity and metabolic syndrome. Laparoscopic Roux-en-Y gastric bypass (LRYGB) may represent a surgical approach which addresses both severe obesity and BE. LRYGB diverts bile away from the gastric pouch and esophagus due to the long Roux limb, and very little acid is produced in the cardia-based gastric pouch. Furthermore, surgically induced weight loss may diminish systemic inflammation, which may contribute to metaplastic changes in the esophagus. Moreover, improved compliance with proton-pump inhibitor therapy, as a consequence of enrolling in a bariatric program, will decrease acid production further. Decreased duodeno-gastro-esophageal reflux should lead to decreased BE. In this study we examine the effect of LRYGB on regression of BE. METHODS AND PROCEDURES: We performed a review of all patients with biopsy proven BE, who underwent LRYGB at our institution. A total of 19 patients were identified. A subset of those patients was identified who had at least 1 year of clinical, endoscopic, or histological data, comprising a total of 14 patients. Seven of these patients had symptoms of gastroesophageal reflux. All 19 patients had short-segment BE. One patient had low-grade dysplasia.
resultsPost-LRYGB, 6 of 14 (42.9%) patients had histologic regression of BE to normal esophageal mucosa, with no evidence of ongoing BE. 13 of 14 patients (92.8%) reported compliance with continuing PPI therapy for at least the first year after surgery. Body mass index for the group of 14 patients improved from 46.6 to 30.3 kg/m
conclusionsWe recommend LRYGB as an effective combined bariatric and anti-reflux surgical procedure for patients with severe obesity and BE. In short-term follow-up, LRYGB achieved endoscopic and histologic regression to normal mucosa in a substantial number of the patients in our series. Long-term follow-up for patients with BE according to standard surveillance protocols is still recommended.
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