Evidence map›Paper›PMID 28779148›Full record

ArticleScientific reports2017

Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ.

Neus Solé-Morata, Patricia Villaescusa, Carla García-Fernández, Neus Font-Porterias, María José Illescas, Laura Valverde, Francesca Tassi, Silvia Ghirotto, Claude Férec, Karen Rouault and 7 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  8. The diverse genetic origins of a Classical period Greek army.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
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  13. Phylogeographic review of Y chromosome haplogroups in Europe.International journal of legal medicine · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Neus Solé-MorataInstitut de Biologia Evolutiva (CSIC-UPF), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.ORCID 0000-0003-0433-0843
Patricia VillaescusaBIOMICs Research Group, Lascaray Research Center, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain.ORCID 0000-0001-6010-0343
Carla García-FernándezInstitut de Biologia Evolutiva (CSIC-UPF), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Neus Font-PorteriasInstitut de Biologia Evolutiva (CSIC-UPF), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
María José IllescasBIOMICs Research Group, Lascaray Research Center, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain.
Laura ValverdeBIOMICs Research Group, Lascaray Research Center, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain.
Francesca TassiDipartimento di Scienze della Vita e Biotecnologie, Università di Ferrara, Ferrara, Italy.
Silvia GhirottoDipartimento di Scienze della Vita e Biotecnologie, Università di Ferrara, Ferrara, Italy.
Claude FérecInserm, UMR 1078, Brest, France.
Karen RouaultInserm, UMR 1078, Brest, France.
Susana Jiménez-MorenoForensic and Legal Medicine Area, Department of Pathology and Surgery, University Miguel Hernández, Elche, Spain.
Begoña Martínez-JarretaDepartment of Forensic Medicine, University of Zaragoza, Zaragoza, Spain.
Maria Fátima PinheiroForensic Genetics Department, National Institute of Legal Medicine and Forensic Sciences, Porto, Portugal.
María T ZarrabeitiaUnit of Legal Medicine, University of Cantabria, Santander, Spain.
Ángel CarracedoGenomic Medicine Group, CIBERER- University of Santiago de Compostela, Galician Foundation of Genomic Medicine (SERGAS), Santiago de Compostela, Spain.
Marian M de PancorboBIOMICs Research Group, Lascaray Research Center, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain.
Francesc CalafellInstitut de Biologia Evolutiva (CSIC-UPF), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain. francesc.calafell@upf.edu.ORCID 0000-0002-1083-9438

Funding

European Research Council 295733
6 · The paper itself

Abstract

Haplogroup R1b-M269 comprises most Western European Y chromosomes; of its main branches, R1b-DF27 is by far the least known, and it appears to be highly prevalent only in Iberia. We have genotyped 1072 R1b-DF27 chromosomes for six additional SNPs and 17 Y-STRs in population samples from Spain, Portugal and France in order to further characterize this lineage and, in particular, to ascertain the time and place where it originated, as well as its subsequent dynamics. We found that R1b-DF27 is present in frequencies ~40% in Iberian populations and up to 70% in Basques, but it drops quickly to 6-20% in France. Overall, the age of R1b-DF27 is estimated at ~4,200 years ago, at the transition between the Neolithic and the Bronze Age, when the Y chromosome landscape of W Europe was thoroughly remodeled. In spite of its high frequency in Basques, Y-STR internal diversity of R1b-DF27 is lower there, and results in more recent age estimates; NE Iberia is the most likely place of origin of DF27. Subhaplogroup frequencies within R1b-DF27 are geographically structured, and show domains that are reminiscent of the pre-Roman Celtic/Iberian division, or of the medieval Christian kingdoms.

Indexed as

AllelesChromosomes, Human, YGenetics, PopulationHaplotypesGene FrequencyGenetic VariationHumansMalePhylogenyPolymorphism, Single NucleotideWhite People

Identifiers

PMID28779148
PMCPMC5544771

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.