Evidence map›Paper›PMID 28779078›Full record

ArticleScientific reports2017

Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus.

Varahalarao Vadlapudi, Nabajyoti Borah, Kanaka Raju Yellusani, Sriramya Gade, Prabhakar Reddy, Maheshwari Rajamanikyam, Lakshmi Narasimha Santosh Vempati, Satya Prakash Gubbala, Pankaj Chopra, Suryanarayana Murty Upadhyayula and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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  11. Effect of Mn(II) and Co(II) on Anti-Pharmaceuticals (Basel, Switzerland) · 2024
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  17. Antiparasitic Activities of Compounds Isolated fromAntibiotics (Basel, Switzerland) · 2023
    Article
  18. Article
  19. Metabolic Plasticity ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Varahalarao VadlapudiPharmacology & Toxicology Division, CSIR-Indian Institute of Chemical Technology (IICT), Uppal Road, Tarnaka, Hyderabad, 500 607, India.
Nabajyoti BorahPharmacology & Toxicology Division, CSIR-Indian Institute of Chemical Technology (IICT), Uppal Road, Tarnaka, Hyderabad, 500 607, India.
Kanaka Raju YellusaniPharmacology & Toxicology Division, CSIR-Indian Institute of Chemical Technology (IICT), Uppal Road, Tarnaka, Hyderabad, 500 607, India.
Sriramya GadePharmacology & Toxicology Division, CSIR-Indian Institute of Chemical Technology (IICT), Uppal Road, Tarnaka, Hyderabad, 500 607, India.
Prabhakar ReddyPharmacology & Toxicology Division, CSIR-Indian Institute of Chemical Technology (IICT), Uppal Road, Tarnaka, Hyderabad, 500 607, India.
Maheshwari RajamanikyamPharmacology & Toxicology Division, CSIR-Indian Institute of Chemical Technology (IICT), Uppal Road, Tarnaka, Hyderabad, 500 607, India.
Lakshmi Narasimha Santosh VempatiPharmacology & Toxicology Division, CSIR-Indian Institute of Chemical Technology (IICT), Uppal Road, Tarnaka, Hyderabad, 500 607, India.
Satya Prakash GubbalaPharmacology & Toxicology Division, CSIR-Indian Institute of Chemical Technology (IICT), Uppal Road, Tarnaka, Hyderabad, 500 607, India.
Pankaj ChopraPharmacology & Toxicology Division, CSIR-Indian Institute of Chemical Technology (IICT), Uppal Road, Tarnaka, Hyderabad, 500 607, India.
Suryanarayana Murty UpadhyayulaNational Institute of Pharmaceutical Education & Research (NIPER-Guwahati), 1st Floor, Institute of Pharmacy, Guwahati Medical College & Hospital, Narakasur Hill top, Guwahati, 781 032, India. director@niperguwahati.ac.in.
Ramars AmanchyDivision of Pharmacology & Toxicology, CSIR-IICT (Indian Institute of Chemical Technology), Ministry of Science & Technology (GOI), Uppal Road, Tarnaka, Hyderabad, Telangana, 500017, India. ramars@iict.res.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus is a genus of ubiquitous fungi that are pathologically & therapeutically important. Aspergillus Secondary Metabolites Database (A2MDB) is a curated compendium of information on Aspergillus & its secondary metabolome. A2MDB catalogs 807 unique non-redundantsecondary metabolites derived from 675 Aspergillus species. A2MDB has a compilation of 100 cellular targets of secondary metabolites, 44 secondary metabolic pathways, 150 electron and light microscopy images of various Aspergillus species. A phylogenetic representation of over 2500 strains has been provided. A2MDB presents a detailed chemical information of secondary metabolites and their mycotoxins. Molecular docking models of metabolite-target protein interactions have been put together. A2MDB also has epidemiological data representing Aspergillosis and global occurrence of Aspergillus species. Furthermore a novel classification of Aspergillosis along with 370 case reports with images, were made available. For each metabolite catalogued, external links to related databases have been provided. All this data is available on A2MDB, launched through Indian Institute of Chemical Technology, Hyderabad, India, as an open resource http://www.iictindia.org/A2MDB . We believe A2MDB is of practical relevance to the scientific community that is in pursuit of novel therapeutics.

Indexed as

Databases, FactualMetabolomeMetabolomicsSecondary MetabolismAspergillosisAspergillusComputational BiologyData MiningEnergy MetabolismHumansMetabolic Networks and PathwaysStructure-Activity Relationship

Identifiers

PMID28779078
PMCPMC5544713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.