ArticlePhysiological genomics2017
Circular RNAs in rat models of cardiovascular and renal diseases.
Article in Physiological genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
25 citing papers in PubMed, 32 citations in OpenAlex.
- CircRNA Profiling Identifies hsa_circRNA_003201 Associated with a Predicted NLRX1-Related Regulatory Network in an Acne-Associated Inflammatory Sebocyte Model.Journal of inflammation research · 2026Article
- Epigenetic Regulation of Ferroptosis in Chronic Kidney Disease: Mechanisms and Implications.Research (Washington, D.C.) · 2025Review
- Circular RNAs as a Diagnostic and Therapeutic Target in Cardiovascular Diseases.International journal of molecular sciences · 2023Review
- circMTND5 Participates in Renal Mitochondrial Injury and Fibrosis by Sponging MIR6812 in Lupus Nephritis.Oxidative medicine and cellular longevity · 2022Article
- Circular RNAs in kidney disease and cancer.Nature reviews. Nephrology · 2021Review
- The emerging role of circular RNAs in cardiovascular diseases.Journal of physiology and biochemistry · 2021Review
- MiRNAs, lncRNAs, and circular RNAs as mediators in hypertension-related vascular smooth muscle cell dysfunction.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Review
- Circular RNAs as Novel Diagnostic Biomarkers and Therapeutic Targets in Kidney Disease.Frontiers in medicine · 2021Review
- Exosomal circ_DLGAP4 promotes diabetic kidney disease progression by sponging miR-143 and targeting ERBB3/NF-κB/MMP-2 axis.Cell death & disease · 2020Article
- Circular RNA in renal diseases.Journal of cellular and molecular medicine · 2020Review
- Hsa_circ_0046159 is involved in the development of chronic thromboembolic pulmonary hypertension.Journal of thrombosis and thrombolysis · 2020Article
- Identification of Candidate Biomarkers for Salt Sensitivity of Blood Pressure by Integrated Bioinformatics Analysis.Frontiers in genetics · 2020Article
- CircNr1h4 regulates the pathological process of renal injury in salt-sensitive hypertensive mice by targeting miR-155-5p.Journal of cellular and molecular medicine · 2020Article
- Hsa_circ_0011385 accelerates the progression of thyroid cancer by targeting miR-361-3p.Cancer cell international · 2020Article
- Circular RNAs in hypertension: challenges and clinical promise.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Review
- Circular RNAs in β-cell function and type 2 diabetes-related complications: a potential diagnostic and therapeutic approach.Molecular biology reports · 2019Review
- Non-coding RNA-Associated ceRNA Networks in a New Contrast-Induced Acute Kidney Injury Rat Model.Molecular therapy. Nucleic acids · 2019Article
- Noncoding RNAs in Hypertension.Hypertension (Dallas, Tex. : 1979) · 2019Review
- Epigenetics and vascular diseases.Journal of molecular and cellular cardiology · 2019Review
- KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis.Cell death & disease · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circular RNAs (circRNAs) have emerged as an important new class of genomic regulatory molecules contributing to the development of various diseases, but their relevance to the development and progression of hypertension remains largely unknown. A major impediment to begin studying circRNAs in rat models of inherited hypertension is that the rat as a valuable model of human diseases lags far behind the mouse and human in providing knowledge on circRNAs. In this study, a genome-wide circRNA profiling was performed from four rat strains that are widely used in hypertension research: the Dahl salt-sensitive rat (S), the Dahl salt-resistant rat (R), the spontaneously hypertensive rat (SHR), and the Wistar Kyoto rat (WKY). Combined hybridization data obtained from these four strains allowed for the identification of 12,846 circRNAs as being expressed in the rat kidneys. Out of these, 318 and 110 circRNAs were differentially expressed with a fold change > 1.5 (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.