Evidence map›Paper›PMID 28778975›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

EHD4 is a novel regulator of urinary water homeostasis.

Shamma S Rahman, Alexandra E J Moffitt, Andrew J Trease, Kirk W Foster, Matthew D Storck, Hamid Band, Erika I Boesen

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shamma S RahmanDepartment of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Alexandra E J MoffittThe Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Andrew J TreaseDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Kirk W FosterDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Matthew D StorckThe Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Hamid BandThe Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, Nebraska, USA; hband@unmc.edu.
Erika I BoesenDepartment of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, Nebraska, USA; erika.boesen@unmc.edu.
University of Nebraska Medical Center · US

Funding

Research Pilot Project ProgramP30GM106397 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI JOHNSON, KEITH R · 2013 to 2017
$4.9M
Targeting Endocytic Recycling of EGF Receptor in Cancer R01CA105489 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAND, HAMID · 2004 to 2014
$3.0M
NCI NIH HHS R01 CA105489NIGMS NIH HHS P30 GM106397
6 · The paper itself

Abstract

The Eps15-homology domain-containing (EHD) protein family comprises 4 members that regulate endocytic recycling. Although the kidney expresses all 4 EHD proteins, their physiologic roles are largely unknown. This study focused on EHD4, which we found to be expressed differentially across nephron segments with the highest expression in the inner medullary collecting duct. Under baseline conditions,

Indexed as

AnimalsAquaporin 2Aquaporin 4Arginine VasopressinCell LineDNA-Binding ProteinsFemaleHomeostasisKidney MedullaMaleMiceMice, Inbred C57BLMice, KnockoutNuclear ProteinsUrineWaterAquaporin 2Aquaporin 4Arginine VasopressinDNA-Binding ProteinsEHD4 protein, mouseNuclear ProteinsWateraquaporin-2aquaporin-4arginine vasopressinendocytic recycling

Identifiers

PMID28778975
PMCPMC5690383
OpenAlexW2745273313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.