Evidence map›Paper›PMID 28778926›Full record

ArticleThe Journal of biological chemistry2017

Selective exclusion and selective binding both contribute to ion selectivity in KcsA, a model potassium channel.

M Lourdes Renart, Estefanía Montoya, A Marcela Giudici, José A Poveda, Asia M Fernández, Andrés Morales, José M González-Ros

Open access · hybridAbstract readComparative Study
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Conductance selectivity of NaProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  5. Article
  6. Modulation of Function, Structure and Clustering of KInternational journal of molecular sciences · 2020
    Review
  7. Why Nature Chose Potassium.Journal of molecular evolution · 2019
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

M Lourdes RenartFrom the Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, 03202 Alicante, Spain and.
Estefanía MontoyaFrom the Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, 03202 Alicante, Spain and.
A Marcela GiudiciFrom the Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, 03202 Alicante, Spain and.
José A PovedaFrom the Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, 03202 Alicante, Spain and.
Asia M FernándezFrom the Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, 03202 Alicante, Spain and.
Andrés MoralesDepartamento de Fisiología, Genética y Microbiología, Universidad de Alicante, 03080 Alicante, Spain.
José M González-RosFrom the Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, 03202 Alicante, Spain and gonzalez.ros@umh.es.
Universitat de Miguel Hernández d'Elx · ESUniversity of Alicante · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The selectivity filter in potassium channels, a main component of the ion permeation pathway, configures a stack of binding sites (sites S1-S4) to which K

Indexed as

Models, MolecularAlgorithmsAmino Acid SubstitutionBacterial ProteinsBinding, CompetitiveBinding SitesCesiumDetergentsGlucosidesHot TemperatureKineticsMutationPotassiumPotassium Channel BlockersPotassium ChannelsProtein DenaturationBacterial ProteinsCesiumDetergentsdodecyl maltosideGlucosidesPotassiumPotassium Channel BlockersPotassium Channelsprokaryotic potassium channelQuaternary Ammonium CompoundsRecombinant Fusion ProteinsRubidiumSodiumtetrabutylammoniumbiophysicsion bindingmembrane proteinpotassium channelprotein stabilityselectivity filter conformationsstructure-function

Identifiers

PMID28778926
PMCPMC5602411
OpenAlexW2742890128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.