Evidence map›Paper›PMID 28778911›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2017

Effect of ovariectomy on intracellular Ca

Hsiang-Yu Yang, Jahn M Firth, Alice J Francis, Anita Alvarez-Laviada, Kenneth T MacLeod

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Sex differences in heart: from basics to clinics.European journal of medical research · 2022
    Review
  6. Article
  7. GPER limits adverse changes to CaFrontiers in physiology · 2022
    Article
  8. Review
  9. The Effect of Estrogen on Intracellular CaJACC. Basic to translational science · 2020
    Article
  10. Estrogen regulation of cardiac cAMP-L-type CaCell communication and signaling : CCS · 2019
    Article
  11. Article
  12. Female Heart Health: Is GPER the Missing Link?Frontiers in endocrinology · 2019
    Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Hsiang-Yu YangNational Heart and Lung Institute, Imperial College London, London, United Kingdom; and.
Jahn M FirthNational Heart and Lung Institute, Imperial College London, London, United Kingdom; and.
Alice J FrancisNational Heart and Lung Institute, Imperial College London, London, United Kingdom; and.
Anita Alvarez-LaviadaNational Heart and Lung Institute, Imperial College London, London, United Kingdom; and.
Kenneth T MacLeodNational Heart and Lung Institute, Imperial College London, London, United Kingdom; and k.t.macleod@imperial.ac.uk.
Imperial College London · GBNational Defense Medical Center · TW

Funding

British Heart Foundation SP/16/2/32004
6 · The paper itself

Abstract

This study addressed the hypothesis that long-term deficiency of ovarian hormones after ovariectomy (OVx) alters cellular Ca

Indexed as

Calcium SignalingOvariectomyAction PotentialsAdrenergic beta-AgonistsAnimalsArrhythmias, CardiacCalciumCalcium Channels, L-TypeDrug ImplantsEstradiolEstrogen Replacement TherapyExcitation Contraction CouplingFemaleGuinea PigsIsoproterenolMyocytes, CardiacAdrenergic beta-AgonistsCalciumCalcium Channels, L-TypeDrug ImplantsEstradiolIsoproterenol17β-estradiolarrhythmiacalcium regulationovariectomy

Identifiers

PMID28778911
PMCPMC5792202
OpenAlexW2744629355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.