ArticleBone2017
Phantomless calibration of CT scans for measurement of BMD and bone strength-Inter-operator reanalysis precision.
Article in Bone, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 115 citations in OpenAlex.
- Romosozumab improves lumbar spine bone mass and bone strength parameters relative to alendronate in postmenopausal women: results from the Active-Controlled Fracture Study in Postmenopausal Women With Osteoporosis at High Risk (ARCH) trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021Trial
- Phantomless calibration of glenoid trabecular bone density: improved accuracy using age-stratified reference tissue densities.JBMR plus · 2026Article
- Improving bone mineral density assessment in total shoulder arthroplasty: assessment of phantom-calibrated Hounsfield units in the glenoid and proximal humerus.JSES international · 2026Article
- Investigating the Influence of Limited CT Scan Coverage Using an Automated Workflow with Biofidelic Sideways Fall FE Models.Annals of biomedical engineering · 2026Article
- Effects of contrast on opportunistic computed tomography vertebral bone mineral density analysis using internal calibration.JBMR plus · 2026Article
- Predictive efficacy of phantom-less calibration of computed tomography for cage subsidence after anterior cervical discectomy and fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Combination of artificial intelligence and chest computed tomography to assess bone mineral density.Skeletal radiology · 2026Article
- Comparative biomechanical analysis of pedicle screws versus cortical bone trajectory fixation in the treatment of ankylosing spondylitis.European journal of medical research · 2026Article
- Strong correlation between phantomless and inline phantom-based densitometric calibration of vertebral properties from CT scans of healthy volunteers.Frontiers in bioengineering and biotechnology · 2026Article
- Application of virtual monochromatic images in bone mineral density measurements: a phantom study.Scientific reports · 2025Article
- Using Phantomless QCT for evaluating BMD evolution in maintenance hemodialysis patients.Scientific reports · 2025Article
- Establishing the effect of computed tomography reconstruction kernels on the measure of bone mineral density in opportunistic osteoporosis screening.Scientific reports · 2025Article
- Reverse Shoulder Arthroplasty Baseplate Stability Is Affected by Bone Density and the Type and Amount of Augmentation.Bioengineering (Basel, Switzerland) · 2025Article
- Computed tomography provides a "one-stop-shop" targeted analysis for coronary artery calcification and osteoporosis: a review.Frontiers in endocrinology · 2025Review
- Bisphosphonate Use and Risk of Atypical Femoral Fractures: A Danish Case-Cohort Study With Blinded Radiographic Review.The Journal of clinical endocrinology and metabolism · 2024Article
- Osteoporosis treatment prevents hip fracture similarly in both sexes: the FOCUS observational study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Observational
- Asynchronous calibration of a CT scanner for bone mineral density estimation: sources of error and correction.JBMR plus · 2024Article
- Side specific differences of Hounsfield-Units in the osteoporotic lumbar spine.Journal of spine surgery (Hong Kong) · 2024Article
- Phantomless calibration of CT scans for hip fracture risk prediction in silico: Comparison with phantom-based calibration.PloS one · 2024Article
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Patient-specific phantomless calibration of computed tomography (CT) scans has the potential to simplify and expand the use of pre-existing clinical CT for quantitative bone densitometry and bone strength analysis for diagnostic and monitoring purposes. In this study, we quantified the inter-operator reanalysis precision errors for a novel implementation of patient-specific phantomless calibration, using air and either aortic blood or hip adipose tissue as internal calibrating reference materials, and sought to confirm the equivalence between phantomless and (traditional) phantom-based measurements. CT scans of the spine and hip for 25 women and 15 men (mean±SD age of 67±9years, range 41-86years), one scan per anatomic site per patient, were analyzed independently by two analysts using the VirtuOst software (O.N. Diagnostics, Berkeley, CA). The scans were acquired at 120kVp, with a slice thickness/increment of 3mm or less, on nine different CT scanner models across 24 different scanners. The main parameters assessed were areal bone mineral density (BMD) at the hip (total hip and femoral neck), trabecular volumetric BMD at the spine, and vertebral and femoral strength by finite element analysis; other volumetric BMD measures were also assessed. We found that the reanalysis precision errors for all phantomless measurements were ≤0.5%, which was as good as for phantom calibration. Regression analysis indicated equivalence of the phantom- versus phantomless-calibrated measurements (slope not different than unity, R
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.