ArticleJournal of neuroimmunology2017
Tumor necrosis factor-alpha -863C/A polymorphism is associated with Guillain-Barré syndrome in Bangladesh.
Article in Journal of neuroimmunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 16 citations in OpenAlex.
- Association of mannose-binding lectin 2 gene polymorphisms with Guillain-Barré syndrome.Scientific reports · 2022Article
- Axonal variants of Guillain-Barré syndrome: an update.Journal of neurology · 2021Review
- A review of the role of genetic factors in Guillain-Barré syndrome.Journal of molecular neuroscience : MN · 2021Review
- Toll-like receptor-4 299Gly allele is associated with Guillain-Barré syndrome in Bangladesh.Annals of clinical and translational neurology · 2019Article
- Lack of association between single-nucleotide polymorphisms of pro- and anti-inflammatory cytokines and HTLV-1-associated myelopathy / tropical spastic paraparesis development in patients from Rio de Janeiro, Brazil.BMC infectious diseases · 2018Article
- Guillain-Barré syndrome, transverse myelitis and infectious diseases.Cellular & molecular immunology · 2018Review
- Tumor Necrosis Factor-α, CD1A and CD1E Genetic Polymorphisms in Guillain-Barré Syndrome: A Study from India.Annals of Indian Academy of NeurologyArticle
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10 authors at 3 institutions in 2 countries.
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Abstract
Guillain-Barré syndrome (GBS) is a post-infectious autoimmune polyneuropathy regulated by pro- and anti-inflammatory cytokines; TNFA polymorphisms may exert immune pathogenic roles in GBS. We assessed TNFA promoter region polymorphisms (-238G/A, -308G/A, -857C/T, -863C/A) in Bangladeshi patients with GBS (n=300) and healthy controls (n=300) by PCR-RFLP and ASO-PCR. TNFA -863CA was significantly associated with GBS disease susceptibility (P=0.0154) and disease severity (P=0.0492). TNFA -238A allele was more frequent among anti-ganglioside (GM1) antibody-positive patients (P=0.0092) and -863AA associated with AMAN subtype of GBS (P=0.0398). TNFA -863C/A may contribute to GBS severity and pathogenesis in Bangladeshi patients.
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