Evidence map›Paper›PMID 28778292›Full record

ReviewCritical care nursing clinics of North America2017

Balance Between the Proinflammatory and Anti-Inflammatory Immune Responses with Blood Transfusion in Sepsis.

Teresa C Rice, Amanda M Pugh, Charles C Caldwell, Barbara St Pierre Schneider

Open access · greenAbstract readReview
In one paragraph

Review in Critical care nursing clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Immunomodulatory Effects of Blood Transfusion on Tumor Size, Metastasis, and Survival in Experimental Fibrosarcoma.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Teresa C RiceDivision of Research, Department of Surgery, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.
Amanda M PughDivision of Research, Department of Surgery, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.
Charles C CaldwellDivision of Research, Department of Surgery, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.
Barbara St Pierre SchneiderThe Tony and Renee Marlon Angel Network Professorship, School of Nursing, University of Nevada, Las Vegas, 4505 South Maryland Parkway, Box 453018, Las Vegas, NV 89154-3018, USA. Electronic address: barbara.stpierreschneider@unlv.edu.
University of Cincinnati Medical Center · USUniversity of Nevada, Las Vegas · US

Funding

HOST RESPONSE TO TRAUMA RESEARCH TRAINING PROGRAMT32GM008478 · NIGMS · UNIVERSITY OF CINCINNATI · PI TIMOTHY A PRITTS, BASILIA ZINGARELLI · 1993 to 2026
$6.7M
Neutrophil-derived microparticle generation and immune impact during sepsisR01GM100913 · NIGMS · UNIVERSITY OF CINCINNATI · PI CALDWELL, CHARLES C. · 2013 to 2016
$1.2M
NIGMS NIH HHS R01 GM100913NIGMS NIH HHS T32 GM008478
6 · The paper itself

Abstract

Blood product transfusion may exacerbate the initial immunosuppressive response of sepsis. Nurses and other patient care providers must be diligent in recognizing and managing a worsening immune status, using flow cytometry to monitor patients' immune status. This type of monitoring may be instrumental in reducing morbidity and mortality in persons with sepsis. This article discusses the recent literature on the associated inflammatory responses that occur with blood transfusion and provides an analysis of alterations in key inflammatory pathways in response to transfusion in a sepsis population.

Indexed as

InflammationTransfusion ReactionCritical Care NursingCytokinesHumansImmunomodulationImmunosuppression TherapySepsisCytokinesBlood transfusionCytokinesImmunosuppressionInflammationLeukocyte reductionSepsis

Identifiers

PMID28778292
PMCPMC5611836
OpenAlexW2667640022

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.