Evidence map›Paper›PMID 28778218›Full record

Trial reportBMC musculoskeletal disorders2017

The effect of targeted treatment on people with patellofemoral pain: a pragmatic, randomised controlled feasibility study.

Benjamin T Drew, Philip G Conaghan, Toby O Smith, James Selfe, Anthony C Redmond

Open access · goldAbstract readComparative StudyPragmatic Clinical TrialRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC musculoskeletal disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Benjamin T DrewLeeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Chapeltown Rd, Leeds, LS7 4SA, UK.ORCID http://orcid.org/0000-0002-2029-0389
Philip G ConaghanNIHR Leeds Biomedical Research Centre, Leeds, UK.
Toby O SmithSchool of Health Sciences, University of East Anglia, Norwich, UK.
James SelfeDepartment of Health Professions, Manchester Metropolitan University, Manchester, UK.
Anthony C RedmondLeeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Chapeltown Rd, Leeds, LS7 4SA, UK. A.Redmond@leeds.ac.uk.
Chapel Allerton Hospital · GBManchester Metropolitan University · GBNIHR Leeds Musculoskeletal Biomedical Research Unit · GBUniversity of East Anglia · GBUniversity of Leeds · GB

Funding

Department of Health CDRF-2013-04-044
6 · The paper itself

Abstract

backgroundTargeted treatment, matched according to specific clinical criteria e.g. hip muscle weakness, may result in better outcomes for people with patellofemoral pain (PFP). However, to ensure the success of future trials, a number of questions on the feasibility of a targeted treatment need clarification. The aim of the study was to explore the feasibility of matched treatment (MT) compared to usual care (UC) management for a subgroup of people with PFP determined to have hip weakness and to explore the mechanism of effect for hip strengthening.

methodsIn a pragmatic, randomised controlled feasibility study, 24 participants with PFP (58% female; mean age 29 years) were randomly allocated to receive either MT aimed specifically at hip strengthening, or UC over an eight-week period. The primary outcomes were feasibility outcomes, which included rates of adherence, attrition, eligibility, missing data and treatment efficacy. Secondary outcomes focused on the mechanistic outcomes of the intervention, which included hip kinematics.

resultsConversion to consent (100%), missing data (0%), attrition rate (8%) and adherence to both treatment and appointments (>90%) were deemed successful endpoints. The analysis of treatment efficacy showed that the MT group reported a greater improvement for the Global Rating of Change Scale (62% vs. 9%) and the Anterior Knee Pain Scale (-5.23 vs. 1.18) but no between-group differences for either average or worst pain. Mechanistic outcomes showed a greatest reduction in peak hip internal rotation angle for the MT group (13.1% vs. -2.7%).

conclusionThis feasibility study indicates that a definitive randomised controlled trial investigating a targeted treatment approach is achievable. Findings suggest the mechanism of effect of hip strengthening may be to influence kinematic changes in hip function in the transverse plane.

trial registrationThis study was registered retrospectively. ISRCTN74560952 . Registration date: 2017-02-06.

Indexed as

AdultBiomechanical PhenomenaFeasibility StudiesFemaleHipHumansMaleMuscle, SkeletalMuscle StrengthMuscle WeaknessPain ManagementPain MeasurementPatellofemoral Pain SyndromePatient ComplianceResistance TrainingTreatment OutcomeHip strengtheningKneePatellofemoral painStrength trainingTherapeutic exercise

Identifiers

PMID28778218
PMCPMC5545020
OpenAlexW2743954295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.