Evidence map›Paper›PMID 28777984›Full record

Trial reportJournal of psychiatric research2017

Comorbid sleep disorders and suicide risk among children and adolescents with bipolar disorder.

Ian H Stanley, Melanie A Hom, Joan L Luby, Paramjit T Joshi, Karen D Wagner, Graham J Emslie, John T Walkup, David A Axelson, Thomas E Joiner

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of psychiatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Risk profiles before suicide mortality in patients with bipolar disorder across the lifespan.European psychiatry : the journal of the Association of European Psychiatrists · 2025
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  6. Article
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  11. Factors Associated With Sleep Disturbance Amongst Youth With Bipolar Disorder.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Ian H StanleyDepartment of Psychology, Florida State University, Tallahassee, FL, USA. Electronic address: stanley@psy.fsu.edu.
Melanie A HomDepartment of Psychology, Florida State University, Tallahassee, FL, USA.
Joan L LubyDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Paramjit T JoshiDivision of Psychiatry and Behavioral Sciences, Children's National Health System, Washington, DC, USA.
Karen D WagnerDepartment of Psychiatry, University of Texas Medical Branch, Galveston, TX, USA.
Graham J EmslieDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA; Division of Child and Adolescent Psychiatry, Children's Medical Center, Dallas, TX, USA.
John T WalkupDepartment of Psychiatry, Weill Cornell Medical College, New York, NY, USA.
David A AxelsonNationwide Children's Hospital Research Institute, The Ohio State University College of Medicine, Columbus, OH, USA.
Thomas E JoinerDepartment of Psychology, Florida State University, Tallahassee, FL, USA.
Florida State University · USChildren's Medical Center · USChildren's National · USCornell University · USNationwide Children's Hospital · USThe University of Texas Medical Branch at Galveston · USWashington University in St. Louis · US

Funding

Treatment of Early Age Mania (TEAM)U01MH064846 · NIMH · WASHINGTON UNIVERSITY · PI GELLER, BARBARA · 2002 to 2008
$4.8M
Treatment of Early Age Mania StudyU01MH064869 · NIMH · JOHNS HOPKINS UNIVERSITY · PI RIDDLE, MARK A · 2002 to 2008
$3.3M
Treatment of Early-Age ManiaU01MH064851 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AXELSON, DAVID A · 2002 to 2008
$2.7M
Treatment of Early Age ManiaU01MH064850 · NIMH · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI WAGNER, KAREN D · 2002 to 2008
$2.7M
Treatment of Early Age Mania (TEAM)U01MH064887 · NIMH · CHILDREN'S RESEARCH INSTITUTE · PI JOSHI, PARAMJIT T. · 2002 to 2008
$2.6M
Treatment of Early Age Mania (TEAM)U01MH064868 · NIMH · WASHINGTON UNIVERSITY · PI LUBY, JOAN L. · 2002 to 2008
$2.4M
METHODOLOGIES FOR TREATMENT STRATEGIESR01MH051481 · NIMH · STANFORD UNIVERSITY · PI LAVORI, PHILIP WILLIAM · 1995 to 2014
$2.3M
Treatment of Early Age Mania (TEAM)U01MH064911 · NIMH · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI EMSLIE, GRAHAM J. · 2002 to 2003
$777k
NIMH NIH HHS R01 MH051481NIMH NIH HHS U01 MH064846NIMH NIH HHS U01 MH064850NIMH NIH HHS U01 MH064851NIMH NIH HHS U01 MH064868NIMH NIH HHS U01 MH064869NIMH NIH HHS U01 MH064887NIMH NIH HHS U01 MH064911
6 · The paper itself

Abstract

Children and adolescents with bipolar disorder are at increased risk for suicide. Sleep disturbances are common among youth with bipolar disorder and are also independently implicated in suicide risk; thus, comorbid sleep disorders may amplify suicide risk in this clinical population. This study examined the effects of comorbid sleep disorders on suicide risk among youth with bipolar disorder. We conducted secondary analyses of baseline data from the Treatment of Early Age Mania (TEAM) study, a randomized controlled trial of individuals aged 6-15 years (mean ± SD = 10.2 ± 2.7 years) with DSM-IV bipolar I disorder (N = 379). Sleep disorders (i.e., nightmare, sleep terror, and sleepwalking disorders) and suicide risk were assessed via the WASH-U-KSADS and the CDRS-R, respectively. We constructed uncontrolled logistic regression models as well as models controlling for trauma history, a generalized anxiety disorder (GAD) diagnosis, and depression symptoms. Participants with a current comorbid nightmare disorder versus those without were nearly twice as likely to screen positive for suicide risk in an uncontrolled model and models controlling for trauma history, a GAD diagnosis, and depression symptoms. Neither a current comorbid sleep terror disorder nor a sleepwalking disorder was significantly associated with suicide risk. This pattern of findings remained consistent for both current and lifetime sleep disorder diagnoses. Youth with bipolar I disorder and a comorbid nightmare disorder appear to be at heightened suicide risk. Implications for assessment and treatment are discussed.

Indexed as

DreamsAdolescentBipolar DisorderChildComorbidityFemaleHumansMaleRiskSleep Arousal DisordersSleep Wake DisordersSuicideBipolar disorderNightmaresSleep disturbancesSuicide riskYouth

Identifiers

PMID28777984
PMCPMC5653415
OpenAlexW2741428996

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.