Evidence map›Paper›PMID 28777494›Full record

ReviewThoracic cancer2017

Clinico-radiological features and next generation sequencing of pulmonary epithelioid hemangioendothelioma: A case report and review of literature.

Xiaoyong Mao, Zibin Liang, Fidelis Chibhabha, Wei Ou, Ning Li, Pengfei Xu, Siyu Wang

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Thoracic cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Quantitative imaging in medicine and surgery · 2023
    Article
  7. Review
  8. Article
  9. Case Report:Frontiers in medicine · 2022
    Article
  10. Epithelioid hemangioendothelioma: evaluation byAmerican journal of nuclear medicine and molecular imaging · 2021
    Article
  11. [Research Progress of Pulmonary Epithelioid Hemangioendothelioma].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2019
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Xiaoyong MaoDepartment of Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zibin LiangDepartment of Radiation Oncology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Fidelis ChibhabhaDepartment of Anatomy and Neurobiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Wei OuDepartment of Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Ning LiDepartment of Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Pengfei XuDepartment of Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Siyu WangDepartment of Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Sun Yat-sen University · CNFifth Affiliated Hospital of Sun Yat-sen University · CNState Key Laboratory of Oncology in South ChinaSun Yat-sen University Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelioid hemangioendothelioma is a very rare, vascular, low-grade malignant tumor found in the lungs, liver, bone, and other soft tissues. Most patients with pulmonary epithelioid hemangioendothelioma (PEH) are asymptomatic but usually present with multiple bilateral nodular lesions in the lungs. Currently, surgical lung biopsy, histology, and immunohistochemical methods are essential for diagnosis. However, there is no standard therapy for the treatment for PEH. Our paper describes the clinico-radiologic features and genomics of PEH based on next-generation sequencing (NGS) in a 43-year-old male we encountered. The patient came to the hospital with right chest pain. After investigation, a lesion in the middle lobe of the right lung was found, together with smaller multiple lesions in both lungs. After resection of the lesion, histopathological analysis showed positive findings for PEH. The patient's blood and tumor tissue were sent for NGS analysis for further investigation. Results from the analysis revealed mutations of multiple genes. The information obtained from the genomic analysis of PEH using NGS may be significant for the planning and monitoring of treatment for this disease.

Indexed as

AdultChest PainHemangioendothelioma, EpithelioidHigh-Throughput Nucleotide SequencingHumansLung NeoplasmsMaleMutationSequence Analysis, DNAIntravascular bronchoalveolar tumorlobectomynext-generation sequencingpulmonary epithelioid hemangioendotheliomawedge resection

Identifiers

PMID28777494
PMCPMC5668507
OpenAlexW2743357335

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.