ArticleThe Journal of physiology2018
Hypercapnia-induced active expiration increases in sleep and enhances ventilation in unanaesthetized rats.
Article in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 43 citations in OpenAlex.
- Homeostatic coupling of cortical and brainstem delta rhythms in sleeping infant rats.bioRxiv : the preprint server for biology · 2026Article
- Forgotten muscle: diaphragm and sudden infant death syndrome.World journal of pediatrics : WJP · 2026Article
- Erythroid anion exchanger-1 (SLC4A1) modulates carbonic anhydrase inhibitor acetazolamide on respiration.Frontiers in physiology · 2026Article
- Review
- Respiratory and Metabolic Effects of Active Expiration in Freely Behaving Rats.Acta physiologica (Oxford, England) · 2025Article
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- Cholinergic modulation of upper airway control: maturational changes and mechanisms at cellular and synaptic levels.Journal of neurophysiology · 2025Review
- Hypercapnia impacts neural drive and timing of diaphragm neuromotor control.Journal of neurophysiology · 2024Article
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- Exercise derived myokine irisin as mediator of cardiorespiratory, metabolic and thermal adjustments during central and peripheral chemoreflex activation.Scientific reports · 2024Article
- Neuromotor control of spontaneous quiet breathing in awake rats evaluated by assessments of diaphragm EMG stationarity.Journal of neurophysiology · 2023Article
- Neural bases for the genesis and COFrontiers in neuroscience · 2023Article
- Analyzing the brainstem circuits for respiratory chemosensitivity in freely moving mice.eLife · 2022Article
- Central respiratory chemoreception.Handbook of clinical neurology · 2022Review
- Respiratory disturbances and high risk of sudden death in the neonatal connexin-36 knockout mouse.Physiological reports · 2021Article
- Differential modulation of active expiration during hypercapnia by the medullary raphe in unanesthetized rats.Pflugers Archiv : European journal of physiology · 2020Article
- Inhibitory control of active expiration by the Bötzinger complex in rats.The Journal of physiology · 2020Article
- Article
- Article
- Modulation of hypercapnic respiratory response by cholinergic transmission in the commissural nucleus of the solitary tract.Pflugers Archiv : European journal of physiology · 2020Article
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4 authors at 1 institution in 1 country.
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Abstract
key pointsExpiratory muscles (abdominal and thoracic) can be recruited when respiratory drive increases under conditions of increased respiratory demand such as hypercapnia. Studying hypercapnia-induced active expiration in unanaesthetized rats importantly contributes to the understanding of how the control system is integrated in vivo in freely moving animals. In unanaesthetized rats, hypercapnia-induced active expiration was not always recruited either in wakefulness or in sleep, suggesting that additional factors influence the recruitment of active expiration. The pattern of abdominal muscle recruitment varied in a state-dependent manner with active expiration being more predominant in the sleep state than in quiet wakefulness. Pulmonary ventilation was enhanced in periods with active expiration compared to periods without it. ABSTRACT: Expiration is passive at rest but becomes active through recruitment of abdominal muscles under increased respiratory drive. Hypercapnia-induced active expiration has not been well explored in unanaesthetized rats. We hypothesized that (i) CO
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