Evidence map›Paper›PMID 28776580›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2018

Effect of Citalopram on Emotion Processing in Humans: A Combined 5-HT

Sudhakar Selvaraj, Chris Walker, Danilo Arnone, Bo Cao, Paul Faulkner, Philip J Cowen, Jonathan P Roiser, Oliver Howes

Open access · bronzeAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 60 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Review
  10. Review
  11. Lateralization of the 5-HTAmino acids · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Advances in simultaneous PET/MR for imaging neuroreceptor function.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Review
  17. Review
  18. Article
  19. Cognitive Control as a 5-HTFrontiers in psychology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Sudhakar SelvarajDepartment of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA.
Chris WalkerDepartment of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0000-0002-1042-075X
Danilo ArnoneInstitute of Psychiatry, King's College London, Centre for Affective Disorders, London, UK.
Bo CaoDepartment of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0000-0003-3401-6900
Paul FaulknerSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.
Philip J CowenDepartment of Psychiatry, University of Oxford, Oxford, UK.
Jonathan P RoiserInstitute of Cognitive Neuroscience, University College London, London, UK.
Oliver HowesMedical Research Council London Institute of Medical Sciences, Hammersmith Hospital, London, UK.
King's College London · GBThe University of Texas Health Science Center at Houston · USHammersmith Hospital · GBUniversity College London · GBUniversity of California, Los Angeles · USUniversity of Oxford · GB

Funding

Academy of Medical Sciences SGL006\1020Academy of Medical Sciences SGL008\1001Medical Research Council G0700995Medical Research Council G0701421Medical Research Council MC_U120097115Medical Research Council MR/K022202/1Medical Research Council MR/N026063/1Wellcome Trust 094849
6 · The paper itself

Abstract

A subset of patients started on a selective serotonin reuptake inhibitor (SSRI) initially experience increased anxiety, which can lead to early discontinuation before therapeutic effects are manifest. The neural basis of this early SSRI effect is not known. Presynaptic dorsal raphe neuron (DRN) 5-HT

Indexed as

BrainBrain MappingCitalopramCross-Over StudiesEmotionsFacial RecognitionHumansMagnetic Resonance ImagingMiddle AgedMultimodal ImagingPositron-Emission TomographyPsychotropic DrugsReceptor, Serotonin, 5-HT1ASelective Serotonin Reuptake InhibitorsSingle-Blind MethodCitalopramHTR1A protein, humanPsychotropic DrugsReceptor, Serotonin, 5-HT1ASelective Serotonin Reuptake Inhibitors

Identifiers

PMID28776580
PMCPMC5693328
OpenAlexW2743855088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.