ArticleNeuroradiology2017
Infarct fogging on immediate postinterventional CT-a not infrequent occurrence.
Article in Neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- The early fogging effect in cerebral infarction - a case report and review of the literature.BMC neurology · 2026Review
- Transient ischemic attacks presenting as hemiballismus due to carotid stenosis: Evidence indicating a blood-brain barrier defect in the subthalamic nucleus.Dusunen adam : Bakirkoy Ruh ve Sinir Hastaliklari Hastanesi yayin organi · 2024Article
- Recanalization status and temporal evolution of early ischemic changes following stroke thrombectomy.European stroke journal · 2024Article
- Article
- Smart Visualization of Medical Images as a Tool in the Function of Education in Neuroradiology.Diagnostics (Basel, Switzerland) · 2022Article
- Pseudonormalisation of a subacute infarct following recent intravenous contrast administration.BMJ case reports · 2022Article
- Appearance of cerebral infarct fogging on CT perfusion.Radiology case reports · 2019Article
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Authors and funding
5 authors.
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Abstract
purposeA pseudo-normalization of infarcted brain parenchyma, similar to the "fogging effect" which usually occurs after 2-3 weeks, can be observed on CT performed immediately after endovascular stroke treatment (EST). Goal of this study was to analyze the incidence of this phenomenon and its evolution on follow-up imaging.
methodsOne hundred fifty-two patients in our database of 949 patients, who were treated for acute stroke between January 2010 and January 2015, fulfilled the inclusion criteria of (a) EST for an acute stroke in the anterior circulation, (b) an ASPECT-score < 10 on pre-interventional CT, and (c) postinterventional CT imaging within 4.5 h after the procedure. Two independent reviewers analyzed imaging data of these patients.
resultsTransformation of brain areas from hypoattenuated on pre-interventional CT to isodense on postinterventional CT was seen in 37 patients in a total of 49 ASPECTS areas (Cohen's kappa 0.819; p < 0.001). In 17 patients, the previously hypoattenuated brain areas became isodense, but appeared swollen. In 20 patients (13%), the previously hypodense brain area could not be distinguished from normal brain parenchyma. On follow-up imaging, all isodense brain areas showed signs of infarction.
conclusionPseudo-normalization of infarct hypoattenuation on postinterventional CT is not infrequent. It is most likely caused by contrast leakage in infarcted parenchyma and does not represent salvage of ischemic brain parenchyma.
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