Evidence map›Paper›PMID 28776261›Full record

ReviewPflugers Archiv : European journal of physiology2018

Roles of Na

Christopher J Lingle, Pedro L Martinez-Espinosa, Laura Guarina, Emilio Carbone

Open access · greenAbstract readReview
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Copper (CuPharmaceuticals (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Two firing modes and well-resolved NaPflugers Archiv : European journal of physiology · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Gambierol Blocks a KToxins · 2022
    Article
  18. Article
  19. Pro-arrhythmogenic effects ofParasitology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Christopher J LingleDepartment of Anesthesiology, Washington University School of Medicine in St. Louis, 660 S. Euclid Ave., St.Louis, MO, 63105, USA.
Pedro L Martinez-EspinosaDepartment of Anesthesiology, Washington University School of Medicine in St. Louis, 660 S. Euclid Ave., St.Louis, MO, 63105, USA.
Laura GuarinaDepartment of Drug Science, Laboratory of Cellular and Molecular Neuroscience, N.I.S. Centre, Corso Raffaello 30, 10125, Torino, Italy.
Emilio CarboneDepartment of Drug Science, Laboratory of Cellular and Molecular Neuroscience, N.I.S. Centre, Corso Raffaello 30, 10125, Torino, Italy. emilio.carbone@unito.it.ORCID 0000-0003-2239-6280
University of Turin · ITWashington University in St. Louis · US

Funding

SLO family potassium channels: function and physiologyR35GM118114 · NIGMS · WASHINGTON UNIVERSITY · PI LINGLE, CHRISTOPHER J · 2016 to 2025
$6.9M
The role of FGF-mediated fast inactivation of Nav channels in cell excitabilityR01NS100695 · NINDS · WASHINGTON UNIVERSITY · PI LINGLE, CHRISTOPHER J · 2017 to 2020
$1.4M
Fondazione Telethon GGP15110NIGMS NIH HHS R35 GM118114NINDS NIH HHS R01 NS100695
6 · The paper itself

Abstract

Adrenal chromaffin cells (CCs) are the main source of circulating catecholamines (CAs) that regulate the body response to stress. Release of CAs is controlled neurogenically by the activity of preganglionic sympathetic neurons through trains of action potentials (APs). APs in CCs are generated by robust depolarization following the activation of nicotinic and muscarinic receptors that are highly expressed in CCs. Bovine, rat, mouse, and human CCs also express a composite array of Na

Indexed as

Action PotentialsBiological ClocksAdrenal MedullaAnimalsChromaffin CellsHumansIon ChannelsIon ChannelsAction potentialBurst firingCatecholamine releaseChromaffin cell excitabilityPotassium and calcium channelsSodium channels

Identifiers

PMID28776261
PMCPMC5765858
OpenAlexW2742422162

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.