Evidence map›Paper›PMID 28776228›Full record

ArticleParasitology research2017

Symptoms and risk factors of Cryptosporidium hominis infection in children: data from a large waterborne outbreak in Sweden.

Sara Adler, Micael Widerström, Johan Lindh, Mikael Lilja

Open access · hybridAbstract read
In one paragraph

Article in Parasitology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Red Fox (Pathogens (Basel, Switzerland) · 2025
    Article
  3. Analysis of Reported Cases ofMicroorganisms · 2025
    Article
  4. Review
  5. Eugenol: effective complementary treatment for cryptosporidiosis in experimentally infected mice.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  6. A Community WaterborneInternational journal of environmental research and public health · 2024
    Article
  7. Evidence of the Zoonotic Transmission ofPathogens (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Molecular prevalence ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021
    Article
  10. Article
  11. Article
  12. European journal of microbiology & immunology · 2019
    Review
  13. Substantial prevalence of enteroparasitesEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sara AdlerDepartment of Public Health and Clinical Medicine, Unit of Clinical Research Centre-Östersund, Umeå University, Umeå, Sweden.
Micael WiderströmDepartment of Clinical Microbiology, Unit of Communicable Disease Control and Prevention-Östersund, Umeå University, Umeå, Sweden.
Johan LindhDepartment of Cell and Molecular Biology, BMC, Uppsala University, Uppsala, Sweden.
Mikael LiljaDepartment of Public Health and Clinical Medicine, Unit of Clinical Research Centre-Östersund, Umeå University, Umeå, Sweden. mikael.lilja@regionjh.se.ORCID http://orcid.org/0000-0002-5203-9877
Umeå University · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptosporidium is a major cause of diarrheal disease worldwide. In developing countries, this infection is endemic and in children, associated with growth faltering and cognitive function deficits, with the most severe impact on those aged <2 years. Little has been reported about symptoms and risk factors for children in industrialized countries, although the disease incidence is increasing in such regions. In November 2010, a large waterborne outbreak of C. hominis occurred in the city of Östersund in Sweden. Approximately 27,000 of the 60,000 inhabitants were symptomatic. We aimed to describe duration of symptoms and the risk factors for infection with C. hominis in children aged <15 years in a Western setting. Within 2 months after a boil water advisory, a questionnaire was sent to randomly selected inhabitants of all ages, including 753 children aged <15 years. Those with ≥3 loose stools/day were defined as cases of diarrhoea. The response rate was 70.3%, and 211 children (39.9%) fulfilled the case definition. Mean duration of diarrhoea was 7.5 days (median 6, range 1-80 days). Recurrence, defined as a new episode of diarrhoea after ≥2 days of normal stools, occurred in 52.5% of the cases. Significant risk factors for infection, besides living within the distribution area of the contaminated water plant, included a high level of water consumption, male sex, and a previous history of loose stools. The outbreak was characterized by high attack and recurrence rates, emphasizing the necessity of water surveillance to prevent future outbreaks.

Indexed as

AdolescentChildChild, PreschoolCryptosporidiosisCryptosporidiumDiarrheaDisease OutbreaksFemaleHumansInfantMaleRetrospective StudiesRisk FactorsSurveys and QuestionnairesSwedenWaterborne DiseasesChildrenCryptosporidiosisRisk factorsSymptoms

Identifiers

PMID28776228
PMCPMC5599474
OpenAlexW2743530327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.