ArticleDrugs & aging2017
Potentially Inappropriate Medications and the Time to Full Functional Recovery After Hip Fracture.
Article in Drugs & aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04360746 (The Influence of Clinical Pharmacist on the Quality of Drug Prescribing and Rehabilitation Outcomes in Post-acute Hip Fractured Patients), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Influence of Clinical Pharmacist on the Quality of Drug Prescribing and Rehabilitation Outcomes in Post-acute Hip Fractured Patients
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Potentially inappropriate prescribing and its associations with health-related and system-related outcomes in hospitalised older adults: A systematic review and meta-analysis.British journal of clinical pharmacology · 2021Pooled it
- Real-world evidence of the impact of polypharmacy on mortality and recovery after hip fracture in elderly patients.Scientific reports · 2026Observational
- Article
- Impact of Comorbidities on the Prevalence and Recovery Outcomes in Elderly Patients With Neck of Femur Fractures.Cureus · 2025Article
- Nonopioid analgesic use in older patients admitted for orthopedic rehabilitation.PM & R : the journal of injury, function, and rehabilitation · 2024Article
- Comparing prevalence and types of potentially inappropriate medications among patient groups in a post-acute and secondary care hospital.Scientific reports · 2023Article
- Prolonged use of newly prescribed gabapentin after surgery.Journal of the American Geriatrics Society · 2022Article
- Potentially inappropriate medications are negatively associated with functional recovery in patients with sarcopenia after stroke.Aging clinical and experimental research · 2022Article
- Modified Application of Cardiac Rehabilitation in Older Adults (MACRO) Trial: Protocol changes in a pragmatic multi-site randomized controlled trial in response to the COVID-19 pandemic.Contemporary clinical trials · 2022Article
- Pharmacotherapy and the Role of Pharmacists in Rehabilitation Medicine.Progress in rehabilitation medicine · 2022Review
- The impact of decreasing potentially inappropriate medications on activities of daily living in a convalescent rehabilitation setting.International journal of clinical pharmacy · 2021Observational
- High-Risk Perioperative Medications in the Chinese Elderly Population.Clinical interventions in aging · 2021Article
- Inappropriate medications and physical function: a systematic review.Therapeutic advances in drug safety · 2021Review
- Favorable Functional Recovery and Stem Stability after Hip Arthroplasty with a Short Metaphyseal Stem in Elderly Patients with Osteoporotic Femoral Neck Fractures.Hip & pelvis · 2019Article
- Orthogeriatric treatment reduces potential inappropriate medication in older trauma patients: a retrospective, dual-center study comparing conventional trauma care and co-managed treatment.European journal of medical research · 2019Article
- Impact of Number of Drug Types on Clinical Outcome in Patients with Acute Hip Fracture.The journal of nutrition, health & aging · 2019Article
- Influence of Antipsychotics on Functional Prognosis after Geriatric Hip Fracture.The journal of nutrition, health & aging · 2019Article
- Editorial: Orthogeriatrics and Hip Fractures.The journal of nutrition, health & aging · 2018Article
- The impact of body composition, pain and resilience on physical activity, physical function and physical performance at 2 months post hip fracture.Archives of gerontology and geriatricsObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundOlder adults after hip fracture are at increased risk of being prescribed potentially inappropriate medications, and may be particularly vulnerable to their adverse effects.
objectiveThe objective of this study was to examine the association of potentially inappropriate medication use with the time to full functional recovery within 1 year of hip fracture repair.
methodsWe conducted a secondary analysis of a prospective longitudinal study of eight hospitals in St. Louis, MO, USA. The participants were older adults (n = 477) aged 60 years or older who had undergone surgical repair of a hip fracture free of delirium, dementia or depression at baseline. Drugs at baseline were categorised using the American Geriatrics Society 2012 Beers criteria. The outcome was the Functional Recovery Scale total score measured at four time points during a 12-month period of observation. Cox proportional hazards models examined the time to 95% recovery of function ('full recovery'), adjusting for demographics, cognition, depression, medical co-morbidity, pre-fracture functioning and pain as covariates.
resultsPotentially inappropriate medication use was common following hip fracture, with 51% of participants prescribed at least one potentially inappropriate medication and 17.4% prescribed two or more potentially inappropriate medications. Potentially inappropriate medication use was significantly associated with a longer time to achieve full recovery with a hazard ratio of 0.69 (95% confidence interval 0.52-0.92; p = 0.012) and this association was stronger for two or more potentially inappropriate medications compared with one potentially inappropriate medication (hazard ratio = 0.60; 95% confidence interval 0.40-0.90; p = 0.014).
conclusionPotentially inappropriate medication use was associated with a longer time to full functional recovery in older adults who underwent surgery for a hip fracture, particularly in those using two or more potentially inappropriate medications at baseline.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.