Evidence map›Paper›PMID 28776153›Full record

Trial reportObesity surgery2018

Visual Liver Score to Stratify Non-Alcoholic Steatohepatitis Risk and Determine Selective Intraoperative Liver Biopsy in Obesity.

Geraldine J Ooi, Paul R Burton, Arul Earnest, Cheryl Laurie, William W Kemp, Peter D Nottle, Catriona A McLean, Stuart K Roberts, Wendy A Brown

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Geraldine J OoiCentre for Obesity Research and Education, Central Clinical School, Monash University, Melbourne, Australia. geraldine.ooi@monash.edu.
Paul R BurtonCentre for Obesity Research and Education, Central Clinical School, Monash University, Melbourne, Australia.
Arul EarnestDepartment of Epidemiology, Monash University, Melbourne, Australia.
Cheryl LaurieCentre for Obesity Research and Education, Central Clinical School, Monash University, Melbourne, Australia.
William W KempDepartment of Gastroenterology, The Alfred Hospital, Melbourne, Australia.
Peter D NottleDepartment of General Surgery, The Alfred Hospital, Melbourne, Australia.
Catriona A McLeanDepartment of Pathology, The Alfred Hospital, Melbourne, Australia.
Stuart K RobertsDepartment of Gastroenterology, The Alfred Hospital, Melbourne, Australia.
Wendy A BrownCentre for Obesity Research and Education, Central Clinical School, Monash University, Melbourne, Australia.
The Alfred Hospital · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-alcoholic fatty liver disease (NAFLD) and its progressive form, non-alcoholic steatohepatitis (NASH), are endemic in obesity. We aimed to evaluate the diagnostic accuracy and reproducibility of a simple intraoperative visual liver score to stratify the risk of NASH and NAFLD in obesity and determine the need for liver biopsy.

methodsThis is a prospective cohort study of obese adults undergoing bariatric surgery. The surgical team used a visual liver score to evaluate liver colour, size and surface. This was compared to histology from an intraoperative liver biopsy.

resultsThere were 152 participants, age 44.6 ± 12 years, BMI 45 ± 8.3 kg/m

conclusionsA simple, structured tool based on liver appearance can be a useful and reliable tool for NAFLD risk stratification and identification of patients who would most and least benefit from a biopsy. A normal liver appearance reliably excludes significant liver disease, avoiding the need for liver biopsy in patients otherwise at high clinical risk of NASH.

Indexed as

Bariatric SurgeryAdultBiopsyFemaleHumansIntraoperative PeriodLiverMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseObesityPhysical ExaminationPredictive Value of TestsReproducibility of ResultsResearch DesignRisk AssessmentIntraoperative liver biopsyNon-alcoholic fatty liver diseaseNon-alcoholic steatohepatitisObesityVisual appearance

Identifiers

PMID28776153
OpenAlexW2743095485

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.