Evidence map›Paper›PMID 28776084›Full record

ArticleDiabetologia2017

The association of depressive symptoms and diabetes distress with glycaemic control and diabetes complications over 2 years in newly diagnosed type 2 diabetes: a prospective cohort study.

Khalida Ismail, Calum D Moulton, Kirsty Winkley, John C Pickup, Stephen M Thomas, Roy A Sherwood, Daniel Stahl, Stephanie A Amiel

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetologia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. The bidirectional longitudinal association between depressive symptoms and HbADiabetic medicine : a journal of the British Diabetic Association · 2022
    Pooled it
  3. Trial
  4. Diabetes Distress and its Associated factors among Patients Attending a Tertiary Care Center in Eastern India.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Khalida IsmailDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, SE5 9RJ, UK. khalida.2.ismail@kcl.ac.uk.
Calum D MoultonDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, SE5 9RJ, UK.
Kirsty WinkleyDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, SE5 9RJ, UK.
John C PickupDivision of Diabetes and Nutritional Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Stephen M ThomasDepartment of Diabetes and Endocrinology, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Roy A SherwoodDepartment of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK.
Daniel StahlDepartment of Biostatistics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Stephanie A AmielDivision of Diabetes and Nutritional Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
King's College London · GBGuy's and St Thomas' NHS Foundation Trust · GBKing's College Hospital NHS Foundation Trust · GB

Funding

Department of Health RP-PG-0606-1142
6 · The paper itself

Abstract

aims/hypothesisWe examined the associations between depressive symptoms and diabetes distress with glycaemic control and diabetes complications over 2 years, after diagnosis of type 2 diabetes.

methodsIn a multi-ethnic, primary care cohort (n = 1735) of adults, all with recent (<6 months) diagnosis of type 2 diabetes, we measured the associations between depressive symptoms (Patient Health Questionnaire-9 [PHQ-9] score ≥10) and diabetes distress (Problem Areas in Diabetes [PAID] score ≥40), with change in 2 year HbA

resultsOf the 1651 participants (95.2%) of the total primary care cohort with available baseline PHQ-9 and PAID scores, mean ± SD age was 56.2 ± 11.1 years, 55.1% were men and 49.1% were of non-white ethnicity; 232 (14.1%) and 111 (6.7%) had depressive symptoms and diabetes distress, respectively. After adjustment for confounders, depressive symptoms were not associated with worsening HbA CONCLUSIONS/

interpretationIn the first 2 years of type 2 diabetes, the effect of depressive symptoms and diabetes distress on glycaemic control is minimal. There was, however, an association between depressive symptoms and incidence of macrovascular complications. Elevated innate inflammation may be common to both depression and macrovascular diabetes complications, but these findings require replication.

Indexed as

AdultAgedBlood GlucoseDepressionDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHumansHypoglycemic AgentsMaleMiddle AgedOrthohantavirusProspective StudiesRisk FactorsBlood GlucoseGlycated HemoglobinHypoglycemic AgentsDepressive symptomsDiabetes distressGlycaemic controlInflammationMacrovascular complicationsMicrovascular complicationsType 2 diabetes

Identifiers

PMID28776084
PMCPMC6448879
OpenAlexW2742273479

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.