ArticleFrontiers in human neuroscience2017
Anterior Thalamic High Frequency Band Activity Is Coupled with Theta Oscillations at Rest.
Article in Frontiers in human neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy.Epilepsia · 2026Article
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- Functional connectivity of thalamic nuclei during sensorimotor task-based fMRI at 9.4 Tesla.Frontiers in neuroscience · 2025Article
- Exploring anterior thalamus functional connectivity with cortical regions in prospective memory with ultra-high-field functional MRI.Brain communications · 2025Article
- Targeting papez circuit for cognitive dysfunction- insights into deep brain stimulation for Alzheimer's disease.Heliyon · 2024Review
- Causal oscillations in the visual thalamo-cortical network in sustained attention in ferrets.Current biology : CB · 2024Article
- Neuromodulation of the anterior thalamus: Current approaches and opportunities for the future.Current research in neurobiology · 2023Review
- Catching wandering minds with tapping fingers: neural and behavioral insights into task-unrelated cognition.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Time to retire the serial Papez circuit: Implications for space, memory, and attention.Neuroscience and biobehavioral reviews · 2022Review
- The Functional Interactions between Cortical Regions through Theta-Gamma Coupling during Resting-State and a Visual Working Memory Task.Brain sciences · 2022Article
- The anterior thalamic nuclei and cognition: A role beyond space?Neuroscience and biobehavioral reviews · 2021Review
- The Radically Embodied Conscious Cybernetic Bayesian Brain: From Free Energy to Free Will and Back Again.Entropy (Basel, Switzerland) · 2021Article
- Time to put the mammillothalamic pathway into context.Neuroscience and biobehavioral reviews · 2021Review
- The generation and propagation of the human alpha rhythm.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Neural entrainment and network resonance in support of top-down guided attention.Current opinion in psychology · 2019Review
- Article
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
Abstract
Cross-frequency coupling (CFC) between slow and fast brain rhythms, in the form of phase-amplitude coupling (PAC), is proposed to enable the coordination of neural oscillatory activity required for cognitive processing. PAC has been identified in the neocortex and mesial temporal regions, varying according to the cognitive task being performed and also at rest. PAC has also been observed in the anterior thalamic nucleus (ATN) during memory processing. The thalamus is active during the resting state and has been proposed to be involved in switching between task-free cognitive states such as rest, in which attention is internally-focused, and externally-focused cognitive states, in which an individual engages with environmental stimuli. It is unknown whether PAC is an ongoing phenomenon during the resting state in the ATN, which is modulated during different cognitive states, or whether it only arises during the performance of specific tasks. We analyzed electrophysiological recordings of ATN activity during rest from seven patients who received thalamic electrodes implanted for treatment of pharmacoresistant focal epilepsy. PAC was identified between theta (4-6 Hz) phase and high frequency band (80-150 Hz) amplitude during rest in all seven patients, which diminished during engagement in tasks involving an external focus of attention. The findings are consistent with the proposal that theta-gamma coupling in the ATN is an ongoing phenomenon, which is modulated by task performance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.