Evidence map›Paper›PMID 28775320›Full record

ArticleScientific reports2017

Modulation of activation and inactivation by Ca

Frank J P Kühn, Winking Mathis, Kühn Cornelia, Daniel C Hoffmann, Andreas Lückhoff

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Frank J P KühnInstitute of Physiology, Medical Faculty, RWTH Aachen, D52057, Aachen, Germany. fkuehn@ukaachen.de.
Winking MathisInstitute of Physiology, Medical Faculty, RWTH Aachen, D52057, Aachen, Germany.
Kühn CorneliaInstitute of Physiology, Medical Faculty, RWTH Aachen, D52057, Aachen, Germany.
Daniel C HoffmannInstitute of Physiology, Medical Faculty, RWTH Aachen, D52057, Aachen, Germany.
Andreas LückhoffInstitute of Physiology, Medical Faculty, RWTH Aachen, D52057, Aachen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The archetypal TRPM2-like channel of the sea anemone Nematostella vectensis is gated by ADPR like its human orthologue but additionally exhibits properties of other vertebrate TRPM channels. Thus it can help towards an understanding of gating and regulation of the whole subfamily. To elucidate further the role of Ca

Indexed as

AnimalsBoron CompoundsCalciumCalcium SignalingHumansIon Channel GatingMembrane PotentialsMutationSea AnemonesTRPM Cation Channels2-aminoethyl diphenylborinateBoron CompoundsCalciumTRPM Cation Channels

Identifiers

PMID28775320
PMCPMC5543165

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.