Evidence map›Paper›PMID 28775072›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2017

Lmo2 (LIM-Domain-Only 2) Modulates Sphk1 (Sphingosine Kinase) and Promotes Endothelial Cell Migration.

Gianfranco Matrone, Shu Meng, Qilin Gu, Jie Lv, Longhou Fang, Kaifu Chen, John P Cooke

Open access · bronzeAbstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 26 citations in OpenAlex.

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  14. Fli1Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Molecular mechanisms of regulation of sphingosine kinase 1.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2018
    Review
  20. Reporting Sex and Sex Differences in Preclinical Studies.Arteriosclerosis, thrombosis, and vascular biology · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gianfranco MatroneFrom the Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX.
Shu MengFrom the Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX.
Qilin GuFrom the Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX.
Jie LvFrom the Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX.
Longhou FangFrom the Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX.
Kaifu ChenFrom the Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX.
John P CookeFrom the Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX. jpcooke@houstonmethodist.org.
Houston Methodist · US

Funding

Basic and Translational Research iPSC-based hematologic and vascular therapiesU01HL100397 · NHLBI · STANFORD UNIVERSITY · PI COOKE, JOHN P · 2009 to 2015
$7.4M
NCE-based strategy for nuclear reprogramming and regenerative medicineRC2HL103400 · NHLBI · STANFORD UNIVERSITY · PI COOKE, JOHN P · 2009 to 2010
$2.7M
NHLBI NIH HHS RC2 HL103400NHLBI NIH HHS U01 HL100397
6 · The paper itself

Abstract

objective

conclusionsOur data showed that

Indexed as

Cell MovementNeovascularization, PhysiologicAdaptor Proteins, Signal TransducingAnimalsCell ProliferationEndothelial CellsGene ExpressionHumansHuman Umbilical Vein Endothelial CellsLIM Domain ProteinsPhosphotransferases (Alcohol Group Acceptor)Proto-Oncogene ProteinsSphingosine KinaseTranscription FactorsZebrafishZebrafish ProteinsAdaptor Proteins, Signal TransducingLIM Domain ProteinsLMO2 protein, humanlmo2 protein, zebrafishPhosphotransferases (Alcohol Group Acceptor)Proto-Oncogene ProteinsSphingosine KinaseTranscription FactorsZebrafish ProteinsendotheliumhematopoiesisLmo2migrationSphk1

Identifiers

PMID28775072
PMCPMC5637529
OpenAlexW2745179895

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.