Evidence map›Paper›PMID 28775063›Full record

Observational studyJournal of the American Heart Association2017

Current Management of Hyponatremia in Acute Heart Failure: A Report From the Hyponatremia Registry for Patients With Euvolemic and Hypervolemic Hyponatremia (HN Registry).

Mark E Dunlap, Paul J Hauptman, Alpesh N Amin, Sandra L Chase, Joseph A Chiodo, Jun R Chiong, Joseph F Dasta

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

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  19. Targeting the Trafficking of Kidney Water Channels for Therapeutic Benefit.Annual review of pharmacology and toxicology · 2020
    Review
  20. Evidence for Effective Multiple KFrontiers in pharmacology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Mark E DunlapMetroHealth Campus of Case Western Reserve University, Cleveland, OH mdunlap@metrohealth.org.
Paul J HauptmanSaint Louis University School of Medicine, St Louis, MO.
Alpesh N AminUniversity of California, Irvine, CA.
Sandra L ChaseOtsuka Product Development & Commercialization, Inc.,, Princeton, NJ.
Joseph A ChiodoOtsuka Product Development & Commercialization, Inc.,, Princeton, NJ.
Jun R ChiongLoma Linda University Medical Center, Loma Linda, CA.
Joseph F DastaThe University of Texas at Austin College of Pharmacy, Hutto, TX.
Otsuka (United States) · USAustin College · USLoma Linda University Medical Center · USMetroHealth Medical Center · USSaint Louis University · USUniversity of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHyponatremia (HN) occurs commonly in patients with acute heart failure and confers a worse prognosis. Current HN treatment varies widely, with no consensus. This study recorded treatment practices currently used for patients hospitalized with acute heart failure and HN. METHODS AND

resultsData were collected prospectively from 146 US sites on patients hospitalized with acute heart failure and HN (serum sodium concentration [Na

conclusionsThe most commonly used treatment approaches for HN (fluid restriction and no specific treatment) in acute heart failure increased [Na

Indexed as

Acute DiseaseAdultAgedAntidiuretic Hormone Receptor AntagonistsBenzazepinesCombined Modality TherapyFemaleFluid TherapyHeart FailureHospitalizationHumansHyponatremiaMaleMiddle AgedPractice Patterns, Physicians'RegistriesAntidiuretic Hormone Receptor AntagonistsBenzazepinesSaline Solution, HypertonicTolvaptanacute heart failurefluid restrictionhypertonic salinehyponatremiasalinesodiumtolvaptan

Identifiers

PMID28775063
PMCPMC5586406
OpenAlexW2744829507

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.