Evidence map›Paper›PMID 28775003›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Interference with Gs

Peter Lachmann, Linda Hickmann, Anne Steglich, Moath Al-Mekhlafi, Michael Gerlach, Niels Jetschin, Steffen Jahn, Brigitte Hamann, Monika Wnuk, Kirsten Madsen and 6 more

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. An efficient inducible model for the control of gene expression in renin cells.American journal of physiology. Renal physiology · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Renin Cells, the Kidney, and Hypertension.Circulation research · 2021
    Review
  10. Article
  11. Article
  12. Review
  13. COX-2-derived PGEPflugers Archiv : European journal of physiology · 2018
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 4 countries.

Peter LachmannExperimental Nephrology and Division of Nephrology, Department of Internal Medicine III and.
Linda HickmannExperimental Nephrology and Division of Nephrology, Department of Internal Medicine III and.
Anne SteglichExperimental Nephrology and Division of Nephrology, Department of Internal Medicine III and.
Moath Al-MekhlafiExperimental Nephrology and Division of Nephrology, Department of Internal Medicine III and.
Michael GerlachExperimental Nephrology and Division of Nephrology, Department of Internal Medicine III and.
Niels JetschinExperimental Nephrology and Division of Nephrology, Department of Internal Medicine III and.
Steffen JahnInstitute of Pathology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Brigitte HamannInstitute of Pathology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Monika WnukDepartment of Anatomy, University of Bern, Bern, Switzerland.
Kirsten MadsenDepartment of Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark; and.
Valentin DjonovDepartment of Anatomy, University of Bern, Bern, Switzerland.
Min ChenMetabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda.
Lee S WeinsteinMetabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda.
Bernd HohensteinExperimental Nephrology and Division of Nephrology, Department of Internal Medicine III and.
Christian P M HugoExperimental Nephrology and Division of Nephrology, Department of Internal Medicine III and.
Vladimir T TodorovExperimental Nephrology and Division of Nephrology, Department of Internal Medicine III and vladimir.todorov@ukdd.de.
University of Bern · CHNational Institute of Diabetes and Digestive and Kidney Diseases · USNational Institutes of Health · USTU Dresden · DEUniversity Hospital Carl Gustav Carus · DEUniversity of Southern Denmark · DK

Funding

Role of the Gnas Gene in Metabolic RegulationZIADK043313 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI WEINSTEIN, LEE · 2009 to 2025
$4.9M
6 · The paper itself

Abstract

Intracellular cAMP, the production of which is catalyzed by the

Indexed as

AlbuminuriaAllelesAnimalsCell LineCyclic AMPEndothelium, VascularFemaleGene DeletionGenotypeGlomerular Filtration RateGTP-Binding Protein alpha Subunits, GsHomozygoteHumansHypertrophyJuxtaglomerular ApparatusKidneyCyclic AMPGTP-Binding Protein alpha Subunits, GsReninVascular Endothelial Growth Factor Avascular endothelial growth factor A, mouseCell SignalingendotheliumglomerulopathyPathophysiology of Renal Disease and Progressionrenin angiotensin systemVEGF

Identifiers

PMID28775003
PMCPMC5698073
OpenAlexW2743819996

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.