Evidence map›Paper›PMID 28775002›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Kindlin-2 Association with Rho GDP-Dissociation Inhibitor

Ying Sun, Chen Guo, Ping Ma, Yumei Lai, Fan Yang, Jun Cai, Zhehao Cheng, Kuo Zhang, Zhongzhen Liu, Yeteng Tian and 5 more

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Integrins in the kidney - beyond the matrix.Nature reviews. Nephrology · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. CHILKBP protects against podocyte injury by preserving ZO-1 expression.Cellular and molecular life sciences : CMLS · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Ying SunDepartments of Biology and suny@sustc.edu.cn xiaogz@sustc.edu.cn wucy@sustc.edu.cn.
Chen GuoDepartments of Biology and.
Ping MaDepartments of Biology and.
Yumei LaiDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois; and.
Fan YangDepartments of Biology and.
Jun CaiDepartments of Biology and.
Zhehao ChengDepartments of Biology and.
Kuo ZhangDepartments of Biology and.
Zhongzhen LiuDepartments of Biology and.
Yeteng TianDepartments of Biology and.
Yue ShengDepartments of Biology and.
Ruijun TianShenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, China.
Yi DengDepartments of Biology and.
Guozhi XiaoDepartments of Biology and suny@sustc.edu.cn xiaogz@sustc.edu.cn wucy@sustc.edu.cn.
Chuanyue WuDepartments of Biology and suny@sustc.edu.cn xiaogz@sustc.edu.cn wucy@sustc.edu.cn.
Southern University of Science and Technology · CNRush University Medical Center · US

Funding

Signaling Mechanisms of Focal Adhesion Protein Kindlin-2 in ChondrogenesisR01AR068950 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HUANG, JIAN, WU, CHUANYUE · 2015 to 2019
$2.2M
NIAMS NIH HHS R01 AR068950
6 · The paper itself

Abstract

Alteration of podocyte behavior is critically involved in the development and progression of many forms of human glomerular diseases. The molecular mechanisms that control podocyte behavior, however, are not well understood. Here, we investigated the role of Kindlin-2, a component of cell-matrix adhesions, in podocyte behavior

Indexed as

AlbuminuriaAnimalsApoptosisCell MovementCreatinineCytoskeletal ProteinsDisease ProgressionFemaleFibrosisGenotypeHumansKidney GlomerulusMaleMembrane ProteinsMiceMice, KnockoutCreatinineCytoskeletal ProteinsFERMT3 protein, humankindlin-2 protein, mouseMembrane ProteinsMuscle ProteinsNeoplasm ProteinsNeuropeptidesrac1 GTP-Binding ProteinRAC1 protein, humanRac1 protein, mouserho Guanine Nucleotide Dissociation Inhibitor alphaRNA, Small InterferingKindlin-2podocyteRac1RhoGDIαSlit diaphragms

Identifiers

PMID28775002
PMCPMC5698060
OpenAlexW2743390135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.