Evidence map›Paper›PMID 28774892›Full record

ArticleThe Journal of cell biology2017

Dialogue between centrosomal entrance and exit scaffold pathways regulates mitotic commitment.

Kuan Yoow Chan, Marisa Alonso-Nuñez, Agnes Grallert, Kayoko Tanaka, Yvonne Connolly, Duncan L Smith, Iain M Hagan

Open access · hybridAbstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kuan Yoow ChanCell Division Group, Cancer Research UK Manchester Institute, University of Manchester, Manchester, England, UK KuanYoow.Chan@cruk.manchester.ac.uk.ORCID 0000-0002-5974-1650
Marisa Alonso-NuñezCell Division Group, Cancer Research UK Manchester Institute, University of Manchester, Manchester, England, UK.ORCID 0000-0002-7882-6641
Agnes GrallertCell Division Group, Cancer Research UK Manchester Institute, University of Manchester, Manchester, England, UK.
Kayoko TanakaCell Division Group, Cancer Research UK Manchester Institute, University of Manchester, Manchester, England, UK.ORCID 0000-0002-2905-3603
Yvonne ConnollyBiological Mass Spectrometry Facility, Cancer Research UK Manchester Institute, University of Manchester, Manchester, England, UK.
Duncan L SmithBiological Mass Spectrometry Facility, Cancer Research UK Manchester Institute, University of Manchester, Manchester, England, UK.ORCID 0000-0001-6791-450X
Iain M HaganCell Division Group, Cancer Research UK Manchester Institute, University of Manchester, Manchester, England, UK Iain.Hagan@cruk.manchester.ac.uk.ORCID 0000-0002-5858-9415
University of Manchester · GB

Funding

Cancer Research UK 16406Cancer Research UK C147/A6058
6 · The paper itself

Abstract

The fission yeast scaffold molecule Sid4 anchors the septum initiation network to the spindle pole body (SPB, centrosome equivalent) to control mitotic exit events. A second SPB-associated scaffold, Cut12, promotes SPB-associated Cdk1-cyclin B to drive mitotic commitment. Signals emanating from each scaffold have been assumed to operate independently to promote two distinct outcomes. We now find that signals from Sid4 contribute to the Cut12 mitotic commitment switch. Specifically, phosphorylation of Sid4 by NIMA

Indexed as

MitosisBinding SitesCasein Kinase IdeltaCell Cycle ProteinsCentrosomeCheckpoint Kinase 2Cyclin BMicroscopy, FluorescenceMicrotubule-Associated ProteinsMutationNIMA-Related Kinase 1PhosphoproteinsPhosphorylationProtein BindingProtein Tyrosine PhosphatasesSchizosaccharomycesCasein Kinase IdeltaCds1 protein, S pombeCell Cycle ProteinsCheckpoint Kinase 2Clp1 protein, S. pombeCut12 protein, S pombeCyclin Bfin1 protein, S pombeMicrotubule-Associated ProteinsNIMA-Related Kinase 1PhosphoproteinsProtein Tyrosine PhosphatasesSchizosaccharomyces pombe ProteinsSid4 protein, S pombe

Identifiers

PMID28774892
PMCPMC5584178
OpenAlexW2741011373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.