Evidence map›Paper›PMID 28774889›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

A dynamic ribosomal biogenesis response is not required for IGF-1-mediated hypertrophy of human primary myotubes.

Hannah Crossland, James A Timmons, Philip J Atherton

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hannah CrosslandDivision of Genetics and Molecular Medicine, Guy's Hospital, King's College London, London, United Kingdom; and.
James A TimmonsDivision of Genetics and Molecular Medicine, Guy's Hospital, King's College London, London, United Kingdom; and.
Philip J AthertonSchool of Medicine, Royal Derby Hospital, University of Nottingham, Derby, United Kingdom philip.atherton@nottingham.ac.uk.
University of Nottingham · GBKing's College London · GB

Funding

Arthritis Research UK 19891Medical Research Council G1100015Medical Research Council MR/ K00414X/1Medical Research Council MR/K00414X/1
6 · The paper itself

Abstract

Increased ribosomal DNA transcription has been proposed to limit muscle protein synthesis, making ribosome biogenesis central to skeletal muscle hypertrophy. We examined the relationship between ribosomal RNA (rRNA) production and IGF-1-mediated myotube hypertrophy

Indexed as

BenzothiazolesBlotting, WesternCell NucleusCells, CulturedFemaleHumansHypertrophyInsulin-Like Growth Factor IMaleMuscle Fibers, SkeletalMuscle, SkeletalNaphthyridinesPhosphorylationRibosomesRNA, MessengerTOR Serine-Threonine KinasesBenzothiazolesCX 5461Insulin-Like Growth Factor INaphthyridinesRNA, MessengerTOR Serine-Threonine KinasesmTORRNAskeletal muscle

Identifiers

PMID28774889
PMCPMC5690393
OpenAlexW2745218055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.