ArticleStem cell research & therapy2017
Determination of optimized oxygen partial pressure to maximize the liver regenerative potential of the secretome obtained from adipose-derived stem cells.
Article in Stem cell research & therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 25 citations in OpenAlex.
- Engineered mesenchymal stem cell-derived exosomes: A revolutionary approach to unlocking liver disease treatment.Biochemistry and biophysics reports · 2025Review
- "Cellularity as a predictive tool for mesenchymal stem cell concentration in bone marrow concentrates: Implications for regenerative medicine".Bone reports · 2025Article
- Strategies to improve the therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicle (MSC-EV): a promising cell-free therapy for liver disease.Frontiers in bioengineering and biotechnology · 2023Review
- Eupalinolide O Induces Apoptosis in Human Triple-Negative Breast Cancer Cells via Modulating ROS Generation and Akt/p38 MAPK Signaling Pathway.Journal of oncology · 2022Article
- Mesenchymal Stromal/Stem Cells and Their Extracellular Vesicles Application in Acute and Chronic Inflammatory Liver Diseases: Emphasizing on the Anti-Fibrotic and Immunomodulatory Mechanisms.Frontiers in immunology · 2022Review
- Article
- The adipose-derived mesenchymal stem cell secretome promotes hepatic regeneration in miniature pigs after liver ischaemia-reperfusion combined with partial resection.Stem cell research & therapy · 2021Article
- Harnessing adipose‑derived stem cells to release specialized secretome for the treatment of hepatitis B.International journal of molecular medicine · 2021Article
- Protective Effect of Adipose-Derived Mesenchymal Stem Cell Secretome against Hepatocyte Apoptosis Induced by Liver Ischemia-Reperfusion with Partial Hepatectomy Injury.Stem cells international · 2021Article
- Extracellular Vesicles in the Development of the Non-Alcoholic Fatty Liver Disease: An Update.Biomolecules · 2020Review
- Hepatocyte and mesenchymal stem cell co-transplantation in rats with acute liver failure.Korean journal of transplantation · 2020Article
- A novel antifibrotic strategy utilizing conditioned media obtained from miR-150-transfected adipose-derived stem cells: validation of an animal model of liver fibrosis.Experimental & molecular medicine · 2020Article
- Generation of induced secretome from adipose-derived stem cells specialized for disease-specific treatment: An experimental mouse model.World journal of stem cells · 2020Article
- Ameliorating liver fibrosis in an animal model using the secretome released from miR-122-transfected adipose-derived stem cells.World journal of stem cells · 2019Article
- Isolation of Secretome with Enhanced Antifibrotic Properties from miR-214-Transfected Adipose-Derived Stem Cells.Journal of Korean medical science · 2019Article
- Enhanced Therapeutic Potential of the Secretome Released from Adipose-Derived Stem Cells by PGC-1α-Driven Upregulation of Mitochondrial Proliferation.International journal of molecular sciences · 2019Article
- Antioxidant action of hypoxic conditioned media from adipose-derived stem cells in the hepatic injury of expressing higher reactive oxygen species.Annals of surgical treatment and research · 2019Article
- The mesenchymal stem cell secretome as an acellular regenerative therapy for liver disease.Journal of gastroenterology · 2019Review
- Dental pulp stem cells expressing SIRT1 improve new bone formation during distraction osteogenesis.American journal of translational research · 2019Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA hypoxic-preconditioned secretome from stem cells reportedly promotes the functional and regenerative capacity of the liver more effectively than a control secretome. However, the optimum oxygen partial pressure (pO
methodsWe first determined the cellular alterations in adipose tissue-derived stem cells (ASCs) cultured under different pO
resultsOf all AML12 cells cultured under different pO
conclusionsThe data of this study suggest that the secretome of ASCs cultured under 1% pO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.