Evidence map›Paper›PMID 28774298›Full record

ArticleBMC public health2017

Metabolic syndrome and parental history of cardiovascular disease in young adults in urban Ghana.

Kwame Yeboah, Kennedy Konlan Dodam, Patrick Kormla Affrim, Linda Adu-Gyamfi, Anormah Rashid Bado, Richard N A Owusu Mensah, Afua Bontu Adjei, Ben Gyan

Erratum issuedAbstract read
In one paragraph

Article in BMC public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Family history of cardiovascular disease and its modifiable risk factors and association with offspring risk profile.International journal of cardiology. Cardiovascular risk and prevention · 2026
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  15. Magnitude and Associated Factors of Metabolic Syndrome Among Adult Urban Dwellers of Northern Ethiopia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Kwame YeboahDepartment of Physiology, School of Biomedical & Allied Health Sciences, University of Ghana, P O Box 143, Korle-Bu, Accra, Ghana. kyeboah@ug.edu.gh.ORCID 0000-0001-5240-0645
Kennedy Konlan DodamDepartment of Physiology, School of Biomedical & Allied Health Sciences, University of Ghana, P O Box 143, Korle-Bu, Accra, Ghana.
Patrick Kormla AffrimDepartment of Chemical Pathology, School of Biomedical & Allied Health Sciences, University of Ghana, Accra, Ghana.
Linda Adu-GyamfiDepartment of Medical Biochemistry, School of Biomedical & Allied Health Sciences, University of Ghana, Accra, Ghana.
Anormah Rashid BadoDepartment of Physiology, School of Biomedical & Allied Health Sciences, University of Ghana, P O Box 143, Korle-Bu, Accra, Ghana.
Richard N A Owusu MensahDepartment of Physiology, School of Biomedical & Allied Health Sciences, University of Ghana, P O Box 143, Korle-Bu, Accra, Ghana.
Afua Bontu AdjeiDepartment of Chemical Pathology, School of Biomedical & Allied Health Sciences, University of Ghana, Accra, Ghana.
Ben GyanDepartment of Immunology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.

Funding

Stroke and Cardiovascular Research Training (SCaRT) InstituteD43TW009140 · FIC · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADANU, RICHARD M K, ALABI, SULYMAN BIODUN · 2011 to 2023
$2.5M
FIC NIH HHS D43 TW009140
6 · The paper itself

Abstract

backgroundMetabolic syndrome (MetS) in young adults poses significant cardiovascular diseases (CVD) risk for later years. Parental history of CVDs is known to affect the prevalence of CVD risk in adulthood. In sub-Saharan Africa, the burden of MetS in young adults and its relationship with parental CVDs is largely unknown. We studied the gender-specific prevalence of MetS and its association with parental history of diabetes, hypertension and CVDs in young adults resident in urban Ghana.

methodsIn a cross-sectional design, 364 young adults aged 20-30 years were randomly recruited from students of University of Ghana. A structured questionnaire was used to collect data on demography, lifestyle, medical and parental medical history. Anthropometric indices and blood pressures were measured. Fasting blood samples were collected to measure plasma levels of glucose, lipid profile, urea and creatinine. MetS was defined according to the Joint Scientific Statement criteria.

resultsThe prevalence of MetS was 12.4%, higher in females than male participants (18.4% vs 5.7, p = 0.019). Female participants had higher levels of all the components of MetS than the male participants. Compared to participants with no history of parental CVDs, participants with parental CVDs had a higher proportion of abdominal obesity. A positive history of parental CVDs was associated with increase in odds of MetS [OR (95% CI): 1.23 (1.12-3.04), p = 0.037].

conclusionIn our study population, there is relatively high prevalence of MetS; higher in females compared to male participants. Parental history of CVDs was associated with MetS.

Indexed as

ParentsAdultAnthropometryBlood GlucoseCardiovascular DiseasesCross-Sectional StudiesFemaleGhanaHumansLife StyleLipidsMaleMetabolic SyndromeObesity, AbdominalPrevalenceRisk FactorsBlood GlucoseLipids

Identifiers

PMID28774298
PMCPMC5543583

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.