Evidence map›Paper›PMID 28774279›Full record

ArticleBMC cancer2017

Pretreatment glycemic control status is an independent prognostic factor for cervical cancer patients receiving neoadjuvant chemotherapy for locally advanced disease.

Jing Li, Ni-Ya Ning, Qun-Xian Rao, Rong Chen, Li-Juan Wang, Zhong-Qiu Lin

Abstract read
In one paragraph

Article in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing LiDepartment of Gynecologic Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 102 Western Yanjiang Road, Guangzhou, 510120, People's Republic of China.
Ni-Ya NingDepartment of Obstetrics and Gynecology, People's Hospital of Shaolin District, Luohe, 462300, People's Republic of China.
Qun-Xian RaoDepartment of Gynecologic Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 102 Western Yanjiang Road, Guangzhou, 510120, People's Republic of China.
Rong ChenHealth center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.
Li-Juan WangDepartment of Gynecologic Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 102 Western Yanjiang Road, Guangzhou, 510120, People's Republic of China. wanglijuan_sysu@sina.com.
Zhong-Qiu LinDepartment of Gynecologic Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 102 Western Yanjiang Road, Guangzhou, 510120, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate whether poor glycemic control status has a negative impact on survival outcomes and tumor response to chemotherapy in patients receiving neoadjuvant chemotherapy (NACT) for locally advanced cervical cancer (LACC).

methodsA retrospective cohort study was conducted to examine LACC patients undergoing NACT and radical hysterectomy between 2002 and 2011. Patients were divided into three groups: patients without diabetes mellitus (DM), diabetic patients with good glycemic control, and diabetic patients with poor glycemic control. Hemoglobin A

resultsIn total, 388 patients were included and had a median follow-up time of 39 months (range: 4-67 months). Diabetes mellitus (DM) was diagnosed in 89 (22.9%) patients, only 35 (39.3%) of whom had good glycemic control prior to NACT (HbA

conclusionsPoor glycemic control is an independent predictor of survival and tumor response to chemotherapy for patients receiving NACT for LACC.

Indexed as

Blood GlucoseAdultAgedAged, 80 and overBiomarkersChemotherapy, AdjuvantDiabetes ComplicationsFemaleGlycated HemoglobinHumansKaplan-Meier EstimateMiddle AgedNeoadjuvant TherapyNeoplasm GradingNeoplasm MetastasisNeoplasm StagingBiomarkersBlood GlucoseGlycated HemoglobinCervical cancerDiabetes mellitusHemoglobin A1cNeoadjuvant chemotherapyPrognosis

Identifiers

PMID28774279
PMCPMC5543538

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.