Evidence map›Paper›PMID 28774007›Full record

ArticleMaterials (Basel, Switzerland)2016

Do Dental Resin Composites Accumulate More Oral Biofilms and Plaque than Amalgam and Glass Ionomer Materials?

Ning Zhang, Mary A S Melo, Michael D Weir, Mark A Reynolds, Yuxing Bai, Hockin H K Xu

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. TheBiomaterial investigations in dentistry · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Novel antibacterial low-shrinkage-stress resin-based cement.Dental materials : official publication of the Academy of Dental Materials · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ning ZhangDepartment of Orthodontics, School of Stomatology, Capital Medical University, Beijing 100050, China. dentistzhang112@163.com.
Mary A S MeloDepartment of Endodontics, Periodontics and Prosthodontics, School of Dentistry, University of Maryland, Baltimore, MD 21201, USA. mmelo@umaryland.edu.
Michael D WeirDepartment of Endodontics, Periodontics and Prosthodontics, School of Dentistry, University of Maryland, Baltimore, MD 21201, USA. MWeir@umaryland.edu.
Mark A ReynoldsDepartment of Endodontics, Periodontics and Prosthodontics, School of Dentistry, University of Maryland, Baltimore, MD 21201, USA. MReynolds@umaryland.edu.
Yuxing BaiDepartment of Orthodontics, School of Stomatology, Capital Medical University, Beijing 100050, China. byuxing@263.net.
Hockin H K XuDepartment of Endodontics, Periodontics and Prosthodontics, School of Dentistry, University of Maryland, Baltimore, MD 21201, USA. hxu@umaryland.edu.
University of Maryland, Baltimore · USCapital Medical University · CN

Funding

Development of high performance, caries-inhibiting dental nano-materialsR01DE017974 · NIDCR · UNIVERSITY OF MARYLAND BALTIMORE · PI XU, HUAKUN · 2008 to 2011
$1.0M
NIDCR NIH HHS R01 DE017974
6 · The paper itself

Abstract

A long-time drawback of dental composites is that they accumulate more biofilms and plaques than amalgam and glass ionomer restorative materials. It would be highly desirable to develop a new composite with reduced biofilm growth, while avoiding the non-esthetics of amalgam and low strength of glass ionomer. The objectives of this study were to: (1) develop a protein-repellent composite with reduced biofilms matching amalgam and glass ionomer for the first time; and (2) investigate their protein adsorption, biofilms, and mechanical properties. Five materials were tested: A new composite containing 3% of protein-repellent 2-methacryloyloxyethyl phosphorylcholine (MPC); the composite with 0% MPC as control; commercial composite control; dental amalgam; resin-modified glass ionomer (RMGI). A dental plaque microcosm biofilm model with human saliva as inoculum was used to investigate metabolic activity, colony-forming units (CFU), and lactic acid production. Composite with 3% MPC had flexural strength similar to those with 0% MPC and commercial composite control (

Indexed as

amalgamcaries inhibitiondental compositeglass ionomerhuman saliva microcosm biofilmprotein repellant

Identifiers

PMID28774007
PMCPMC5457238
OpenAlexW2541681986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.