ReviewMaterials (Basel, Switzerland)2016
A Review of PMMA Bone Cement and Intra-Cardiac Embolism.
Review in Materials (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Intracardiac bone cement embolism and cardiac injury: a systematic review of 116 reported cases.Journal of cardiothoracic surgery · 2026Pooled it
- Presentations, management strategies, and outcomes of intracardiac cement embolism following spinal vertebral augmentation: a systematic review of case reports.Journal of orthopaedic surgery and research · 2025Pooled it
- The Comparison between Cemented and Uncemented Hemiarthroplasty in Patients with Femoral Neck Fractures: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Orthopaedic surgery · 2023Pooled it
- Article
- Intracardiac cement embolism after vertebral augmentation.World journal of emergency medicine · 2026Article
- Fatal Intracardiac Embolism Following Cement-Augmented Pedicle Screw Instrumentation: A Case Report.Case reports in cardiology · 2026Article
- Numerical and Experimental Investigation of Parameters in Cement Delivery Through Spinal Implants.Materials (Basel, Switzerland) · 2025Article
- Injectable Self-Polymerizing Hydrogel as Bone Filler for Bone Defect Treatment.Macromolecular bioscience · 2025Article
- Role of Augmentation in the Fixation of Osteoporotic Fractures.Indian journal of orthopaedics · 2025Review
- Cement-Augmented Pedicle Screw Fixation in Patients with Osteoporosis : Safety, Efficacy and Complications.Journal of Korean Neurosurgical Society · 2025Article
- Article
- Warning line for preventing bone cement leakage in surgery involving percutaneous kyphoplasty for osteoporotic vertebral compression fractures.Frontiers in surgery · 2025Article
- Injectable bioactive poly(propylene fumarate) and polycaprolactone based click chemistry bone cement for spinal fusion in rabbits.Journal of biomedical materials research. Part A · 2024Article
- Endovascular treatment of a large bone cement pulmonary embolism: Case report.SAGE open medical case reports · 2024Article
- Impact of Cytogenetic Abnormalities, Induction and Maintenance Regimens on Outcomes After High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma: A Decade-Long Real-World Experience.Journal of hematology · 2023Article
- Extensive Intracardiac Cement Embolism in a Patient Undergoing Workup for Bone Marrow Transplant.Journal of hematology · 2023Article
- Poly(glycerol itaconate) Crosslinking via the aza-Michael Reaction-A Preliminary Research.Materials (Basel, Switzerland) · 2023Article
- Advanced applications of strontium-containing biomaterials in bone tissue engineering.Materials today. Bio · 2023Review
- Article
- Right atrial and pulmonary cement embolization following vertebral laminectomy: An incidental finding.Clinical case reports · 2023Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Percutaneous vertebroplasty procedure is of major importance, given the significantly increasing aging population and the higher number of orthopedic procedures related to vertebral compression fractures. Vertebroplasty is a complex technique involving the injection of polymethylmethacrylate (PMMA) into the compressed vertebral body for mechanical stabilization of the fracture. Our understanding and ability to modify these mechanisms through alterations in cement material is rapidly evolving. However, the rate of cardiac complications secondary to PMMA injection and subsequent cement leakage has increased with time. The following review considers the main effects of PMMA bone cement on the heart, and the extent of influence of the materials on cardiac embolism. Clinically, cement leakage results in life-threatening cardiac injury. The convolution of this outcome through an appropriate balance of complex material properties is highlighted via clinical case reports.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.