ArticleMaterials (Basel, Switzerland)2016
Evaluation of the Antimicrobial Activity of Different Antibiotics Enhanced with Silver-Doped Hydroxyapatite Thin Films.
Article in Materials (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 42 citations in OpenAlex.
- Fabrication of biocidal materials based on the molecular interactions of tetracycline and quercetin with hydroxyapatite viaHeliyon · 2025Article
- Development of super nanoantimicrobials combining AgCl, tetracycline and benzalkonium chloride.Discover nano · 2024Article
- Nanohydroxyapatite/Peptide Composite Coatings on Pure Titanium Surfaces with Nanonetwork Structures Using Oyster Shells.Nanomaterials (Basel, Switzerland) · 2024Article
- Development of Novel Tetracycline and Ciprofloxacin Loaded Silver Doped Hydroxyapatite Suspensions for Biomedical Applications.Antibiotics (Basel, Switzerland) · 2022Article
- Bioactive Coatings Based on Hydroxyapatite, Kanamycin, and Growth Factor for Biofilm Modulation.Antibiotics (Basel, Switzerland) · 2021Article
- Biogenic Silver Nanoparticles Decorated with Methylene Blue Potentiated the Photodynamic Inactivation ofPharmaceutics · 2020Article
- Synthesis and Properties of Zinc-Modified Hydroxyapatite.Journal of functional biomaterials · 2020Article
- Study of physico-chemical properties and in vitro antimicrobial activity of hydroxyapatites obtained from bone calcination.Progress in biomaterials · 2019Article
- Synthesis of silver nanoparticle-decorated hydroxyapatite (HA@Ag) poriferous nanocomposites and the study of their antibacterial activities.RSC advances · 2018Article
- Development of Zinc-Doped Hydroxyapatite by Sol-Gel Method for Medical Applications.Molecules (Basel, Switzerland) · 2018Article
- Cationic Substitutions in Hydroxyapatite: Current Status of the Derived Biofunctional Effects and Their In Vitro Interrogation Methods.Materials (Basel, Switzerland) · 2018Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The inhibitory and antimicrobial effects of silver particles have been known since ancient times. In the last few years, a major health problem has arisen due to pathogenic bacteria resistance to antimicrobial agents. The antibacterial activities of new materials including hydroxyapatite (HAp), silver-doped hydroxyapatite (Ag:HAp) and various types of antibiotics such as tetracycline (T-HAp and T-Ag:HAp) or ciprofloxacin (C-HAp and C-Ag:HAp) have not been studied so far. In this study we reported, for the first time, the preparation and characterization of various thin films based on hydroxyapatite and silver-doped hydroxyapatite combined with tetracycline or ciprofloxacin. The structural and chemical characterization of hydroxyapatite and silver-doped hydroxyapatite thin films has been evaluated by X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). The morphological studies of the HAp, Ag:HAp, T-HAp, T-Ag:HAp, C-HAp and C-Ag:HAp thin solid films were performed using scanning electron microscopy (SEM). In order to study the chemical composition of the coatings, energy dispersive X-ray analysis (EDX) and glow discharge optical emission spectroscopy (GDOES) measurements have been used, obtaining information on the distribution of the elements throughout the film. These studies have confirmed the purity of the prepared hydroxyapatite and silver-doped hydroxyapatite thin films obtained from composite targets containing Ca
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