ArticleMaterials (Basel, Switzerland)2016
Novel Osteointegrative Sr-Substituted Apatitic Cements Enriched with Alginate.
Article in Materials (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- A Modular Biomimetic Preclinical Platform to Elucidate the Interaction Between Cancer Cells and the Bone Metastatic Niche.Journal of functional biomaterials · 2025Article
- Injectable bioactive scaffold able to stimulate oral bone regeneration on demand.Journal of materials science. Materials in medicine · 2025Article
- Antibiotics release by hybrid bone scaffold: relationship between kinetic profiles and scaffold intrinsic features.Frontiers in bioengineering and biotechnology · 2025Article
- Simultaneous Substitution of Fe and Sr in Beta-Tricalcium Phosphate: Synthesis, Structural, Magnetic, Degradation, and Cell Adhesion Properties.Materials (Basel, Switzerland) · 2022Article
- Strontium-doped apatitic bone cements with tunable antibacterial and antibiofilm ability.Frontiers in bioengineering and biotechnology · 2022Article
- Evaluation of Human Bone Marrow Mesenchymal Stromal Cell (MSC) Functions on a Biomorphic Rattan-Wood-Derived Scaffold: A Comparison between Cultured and Uncultured MSCs.Bioengineering (Basel, Switzerland) · 2021Article
- A Review on the Enhancement of Calcium Phosphate Cement with Biological Materials in Bone Defect Healing.Polymers · 2021Review
- Review
- Nature-Inspired Unconventional Approaches to Develop 3D Bioceramic Scaffolds with Enhanced Regenerative Ability.Biomedicines · 2021Review
- Recent Trends in Three-Dimensional Bioinks Based on Alginate for Biomedical Applications.Materials (Basel, Switzerland) · 2020Review
- Innovative Options for Bone Metastasis Treatment: An Extensive Analysis on Biomaterials-Based Strategies for Orthopedic Surgeons.Frontiers in bioengineering and biotechnology · 2020Review
- Innovative Biomaterials for Bone Regrowth.International journal of molecular sciences · 2019Review
- Percutaneous osteoplasty for extraspinal metastases.Journal of interventional medicine · 2018Review
- Injectable hybrid system for strontium local delivery promotes bone regeneration in a rat critical-sized defect model.Scientific reports · 2017Article
- Sr-substituted bone cements direct mesenchymal stem cells, osteoblasts and osteoclasts fate.PloS one · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present work describes the synthesis of novel injectable, self-setting bone cements made of strontium-substituted hydroxyapatite (Sr-HA), obtained by single-phase calcium phosphate precursors doped with different amounts of strontium and enriched with alginate. The addition of alginate improved the injectability, cohesion, and compression strength of the cements, without affecting the hardening process. A Sr-HA cement exhibiting adequate hardening times and mechanical strength for clinical applications was further tested in vivo in a rabbit model, in comparison with a commercial calcium phosphate cement, revealing the maintenance of biomimetic composition and porous microstructure even after one month in vivo, as well as enhanced ability to induce new bone formation and penetration.
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Registered trials
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