Evidence map›Paper›PMID 28773642›Full record

ReviewMaterials (Basel, Switzerland)2016

Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help?

Avudaiappan Maran, Michael J Yaszemski, Ananiy Kohut, Andriy Voronov

Open access · goldAbstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  2. Review
  3. Review
  4. Article
  5. Curcumin Derivative C086 Combined with Cisplatin Inhibits Proliferation of Osteosarcoma Cells.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Avudaiappan MaranDepartment of Orthopedics, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USA. maran.avudai@mayo.edu.
Michael J YaszemskiDepartment of Orthopedics, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USA. yaszemski.michael@mayo.edu.
Ananiy KohutDepartment of Organic Chemistry, Lviv Polytechnic National University, vul. S. Bandery, 12, Lviv 79013, Ukraine. ananiy.kohut@gmail.com.
Andriy VoronovDepartment of Coatings and Polymeric Materials, North Dakota State University, NDSU Dept. 2760, P.O. Box 6050, Fargo, ND 58108-6050, USA. andriy.voronov@ndsu.edu.
Mayo Clinic · USLviv Polytechnic National University · UANorth Dakota State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systematic review of experimental and clinical data on the use of curcumin in the treatment of osteosarcoma is presented. The current status of curcumin's therapeutic potential against bone cancer is analyzed in regard to using polymeric micelles (including recently developed invertible, responsive, micelles) as a platform for curcumin delivery to treat osteosarcoma. The potential of micellar assemblies from responsive macromolecules in a controlled delivery of curcumin to osteosarcoma cells, and the release using a new inversion mechanism is revealed.

Indexed as

bone tumor treatmentcurcumin deliveryinvertible polymer micellesmicellar nanoassemblies

Identifiers

PMID28773642
PMCPMC5456898
OpenAlexW2461307944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.