Evidence map›Paper›PMID 28773609›Full record

ArticleMaterials (Basel, Switzerland)2016

Dedifferentiated Human Articular Chondrocytes Redifferentiate to a Cartilage-Like Tissue Phenotype in a Poly(ε-Caprolactone)/Self-Assembling Peptide Composite Scaffold.

Lourdes Recha-Sancho, Franklin T Moutos, Jordi Abellà, Farshid Guilak, Carlos E Semino

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Functional tissue engineering of articular cartilage for biological joint resurfacing-The 2021 Elizabeth Winston Lanier Kappa Delta Award.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  4. Article
  5. Article
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  7. Article
  8. Article
  9. Article
  10. Review
  11. Culturing Mammalian Cells in Three-dimensional Peptide Scaffolds.Journal of visualized experiments : JoVE · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Lourdes Recha-SanchoTissue Engineering Laboratory, Bioengineering Department, IQS School of Engineering, Ramon Llull University, Via Augusta 390, Barcelona 08017, Spain. lourdesrechas@iqs.url.edu.
Franklin T MoutosCytex Therapeutics Inc., Durham, NC 27705, USA. frank.moutos@cytextherapeutics.com.
Jordi AbellàAnalytical Chemistry Department, Institut Químic de Sarrià, Ramon Llull University, Via Augusta 390, Barcelona 08017, Spain. jordi.abella@iqs.url.edu.
Farshid GuilakCytex Therapeutics Inc., Durham, NC 27705, USA. guilak@wustl.edu.
Carlos E SeminoTissue Engineering Laboratory, Bioengineering Department, IQS School of Engineering, Ramon Llull University, Via Augusta 390, Barcelona 08017, Spain. carlos.semino@iqs.url.edu.
Universitat Ramon Llull · ESCytex Therapeutics (United States) · USInstitut Químic de Sarrià · ESShriners Hospitals for Children - St. Louis · US

Funding

Thermally-Triggered Intra-articular Drug Delivery for OAP01AR050245 · NIAMS · DUKE UNIVERSITY · PI GUILAK, FARSHID · 2003 to 2012
$11.5M
VISCOELASTIC PROPERTIES OF NORMAL AND OA CHONDRONSR01AG015768 · NIA · WASHINGTON UNIVERSITY · PI GUILAK, FARSHID · 1998 to 2022
$7.7M
OBESITY, BIOMECHANICS, AND INFLAMMATION IN OSTEOARTHRITISR01AG046927 · NIA · WASHINGTON UNIVERSITY · PI GUILAK, FARSHID · 2013 to 2023
$3.2M
Mechanical and Osmotic Signaling in ChondrocytesR01AR048182 · NIAMS · DUKE UNIVERSITY · PI GUILAK, FARSHID · 2003 to 2013
$3.0M
Intrinsic Repair of the Knee MeniscusR01AR048852 · NIAMS · DUKE UNIVERSITY · PI GUILAK, FARSHID · 2007 to 2011
$1.4M
NIAMS NIH HHS P01 AR050245NIAMS NIH HHS R01 AR048182NIAMS NIH HHS R01 AR048852NIA NIH HHS R01 AG015768NIA NIH HHS R01 AG046927
6 · The paper itself

Abstract

Adult articular cartilage has a limited capacity for growth and regeneration and, with injury, new cellular or biomaterial-based therapeutic platforms are required to promote repair. Tissue engineering aims to produce cartilage-like tissues that recreate the complex mechanical and biological properties found

Indexed as

3D cell culturebiomimetic materialscartilage tissue engineeringcell differentiationhuman chondrocytes

Identifiers

PMID28773609
PMCPMC5456812
OpenAlexW2444035664

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.