Evidence map›Paper›PMID 28773576›Full record

ArticleMaterials (Basel, Switzerland)2016

Synthesis and Characterization of New Chlorhexidine-Containing Nanoparticles for Root Canal Disinfection.

Ridwan Haseeb, Michael Lau, Max Sheah, Francisco Montagner, Gina Quiram, Kelli Palmer, Mihaela C Stefan, Danieli C Rodrigues

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Antibacterial effect of nano-chlorhexidine onDental research journal · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Antibacterial Hydrogels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Ridwan HaseebDepartment of Bioengineering, University of Texas at Dallas, 800 W Campbell, Richardson, TX 75080, USA. rbh110020@utdallas.edu.
Michael LauDepartment of Bioengineering, University of Texas at Dallas, 800 W Campbell, Richardson, TX 75080, USA. mxl110330@utdallas.edu.
Max SheahDepartment of Bioengineering, University of Texas at Dallas, 800 W Campbell, Richardson, TX 75080, USA. mms097020@utdallas.edu.
Francisco MontagnerDepartment of Conservative Dentistry, Dental School, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos 2492, Porto Alegre-RS 90460-001, Brazil. francisco.montagner@ufrgs.br.
Gina QuiramDepartment of Bioengineering, University of Texas at Dallas, 800 W Campbell, Richardson, TX 75080, USA. gjq140030@utdallas.edu.
Kelli PalmerDepartment of Molecular and Cell Biology, University of Texas at Dallas, 800 W Campbell, Richardson, TX 75080, USA. Kelli.Palmer@utdallas.edu.
Mihaela C StefanDepartment of Bioengineering, University of Texas at Dallas, 800 W Campbell, Richardson, TX 75080, USA. mihaela@utdallas.edu.
Danieli C RodriguesDepartment of Bioengineering, University of Texas at Dallas, 800 W Campbell, Richardson, TX 75080, USA. dxb127430@utdallas.edu.
The University of Texas at Dallas · USUniversidade Federal do Rio Grande do Sul · BR

Funding

Nanoparticles based on histone deacetylase inhibitors for combination treatmentsR21EB019175 · NIBIB · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI OUPICKY, DAVID · 2015 to 2016
$430k
NIBIB NIH HHS R21 EB019175
6 · The paper itself

Abstract

Root canal system disinfection is limited due to anatomical complexities. Better delivery systems of antimicrobial agents are needed to ensure efficient bacteria eradication. The purpose of this study was to design chlorhexidine-containing nanoparticles that could steadily release the drug. The drug chlorhexidine was encapsulated in poly(ethylene glycol)-

Indexed as

chlorhexidinedentin permeabilitydentin tubulesencapsulationnanoparticles

Identifiers

PMID28773576
PMCPMC5456790
OpenAlexW2419270023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.