Evidence map›Paper›PMID 28773528›Full record

ReviewMaterials (Basel, Switzerland)2016

Graphene-Gold Nanoparticles Hybrid-Synthesis, Functionalization, and Application in a Electrochemical and Surface-Enhanced Raman Scattering Biosensor.

Ibrahim Khalil, Nurhidayatullaili Muhd Julkapli, Wageeh A Yehye, Wan Jefrey Basirun, Suresh K Bhargava

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Research Progress on Nanomaterials in SPR Sensors.Nanomaterials (Basel, Switzerland) · 2025
    Review
  6. The Tunable Parameters of Graphene-Based Biosensors.Sensors (Basel, Switzerland) · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ibrahim KhalilInstitute of Postgraduate Studies Building, Nanotechnology & Catalysis Research Centre (NANOCAT), University of Malaya, Kuala Lumpur 50603, Malaysia. ikhalilcu@gmail.com.
Nurhidayatullaili Muhd JulkapliInstitute of Postgraduate Studies Building, Nanotechnology & Catalysis Research Centre (NANOCAT), University of Malaya, Kuala Lumpur 50603, Malaysia. nurhidayatullaili@um.edu.my.
Wageeh A YehyeInstitute of Postgraduate Studies Building, Nanotechnology & Catalysis Research Centre (NANOCAT), University of Malaya, Kuala Lumpur 50603, Malaysia. wdabdoub@um.edu.my.
Wan Jefrey BasirunInstitute of Postgraduate Studies, Department of Chemistry, University of Malaya, Kuala Lumpur 50603, Malaysia. jeff@um.edu.my.
Suresh K BhargavaCentre for Advanced Materials & Industrial Chemistry (CAMIC), School of Applied Sciences, RMIT University, GPO Box 2476, Melbourne 3001, Australia. suresh.bhargava@rmit.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene is a single-atom-thick two-dimensional carbon nanosheet with outstanding chemical, electrical, material, optical, and physical properties due to its large surface area, high electron mobility, thermal conductivity, and stability. These extraordinary features of graphene make it a key component for different applications in the biosensing and imaging arena. However, the use of graphene alone is correlated with certain limitations, such as irreversible self-agglomerations, less colloidal stability, poor reliability/repeatability, and non-specificity. The addition of gold nanostructures (AuNS) with graphene produces the graphene-AuNS hybrid nanocomposite which minimizes the limitations as well as providing additional synergistic properties, that is, higher effective surface area, catalytic activity, electrical conductivity, water solubility, and biocompatibility. This review focuses on the fundamental features of graphene, the multidimensional synthesis, and multipurpose applications of graphene-Au nanocomposites. The paper highlights the graphene-gold nanoparticle (AuNP) as the platform substrate for the fabrication of electrochemical and surface-enhanced Raman scattering (SERS)-based biosensors in diverse applications as well as SERS-directed bio-imaging, which is considered as an emerging sector for monitoring stem cell differentiation, and detection and treatment of cancer.

Indexed as

bioimagingelectrochemical biosensorgraphenegraphene–gold nanoparticleSERS biosensor

Identifiers

PMID28773528
PMCPMC5456764

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.