Evidence map›Paper›PMID 28773259›Full record

ArticleMaterials (Basel, Switzerland)2016

Alendronate Functionalized Mesoporous Bioactive Glass Nanospheres.

Elisa Boanini, Silvia Panseri, Fabiola Arroyo, Monica Montesi, Katia Rubini, Anna Tampieri, Cristian Covarrubias, Adriana Bigi

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elisa BoaniniDepartment of Chemistry "G. Ciamician", University of Bologna, Via Selmi 2, Bologna 40126, Italy. elisa.boanini@unibo.it.
Silvia PanseriInstitute of Science and Technology for Ceramics, National Research Council of Italy, Via Granarolo 64, Faenza 48018, Italy. silvia.panseri@istec.cnr.it.
Fabiola ArroyoLaboratory of Nanobiomaterials, Institute for Research in Dental Sciences, Faculty of Dentistry, University of Chile, Santiago 8380492, Chile. fabiola.arroyo@gmail.com.
Monica MontesiInstitute of Science and Technology for Ceramics, National Research Council of Italy, Via Granarolo 64, Faenza 48018, Italy. monica.montesi@istec.cnr.it.
Katia RubiniDepartment of Chemistry "G. Ciamician", University of Bologna, Via Selmi 2, Bologna 40126, Italy. katia.rubini@unibo.it.
Anna TampieriInstitute of Science and Technology for Ceramics, National Research Council of Italy, Via Granarolo 64, Faenza 48018, Italy. anna.tampieri@istec.cnr.it.
Cristian CovarrubiasLaboratory of Nanobiomaterials, Institute for Research in Dental Sciences, Faculty of Dentistry, University of Chile, Santiago 8380492, Chile. ccovarrubias@odontologia.uchile.cl.
Adriana BigiDepartment of Chemistry "G. Ciamician", University of Bologna, Via Selmi 2, Bologna 40126, Italy. adriana.bigi@unibo.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work we synthesized mesoporous bioactive glass nanospheres (nMBG) with the aim to utilize them as substrates for loading one of the most potent amino-bisphosphonates, alendronate (AL). The results of the chemical and structural characterization show that the nMBG display a relatively high surface area (528 m²/g) and a mean pore volume of 0.63 cm³/g, both of which decrease on increasing alendronate content. It is possible to modulate the amount of AL loaded into the nanospheres up to a maximum value of about 17 wt %.

Indexed as

alendronateanti-cancerbioactive glass nanospheresmesoporousosteoclast inhibition

Identifiers

PMID28773259
PMCPMC5456651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.