Evidence map›Paper›PMID 28772392›Full record

ArticleMaterials (Basel, Switzerland)2017

Numerical Prediction of the Mechanical Failure of the Intervertebral Disc under Complex Loading Conditions.

Gloria Casaroli, Tomaso Villa, Tito Bassani, Nikolaus Berger-Roscher, Hans-Joachim Wilke, Fabio Galbusera

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
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  4. Review
  5. A more realistic disc herniation model incorporating compression, flexion and facet-constrained shear: a mechanical and microstructural analysis. Part I: Low rate loading.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gloria CasaroliLaboratory of Biological Structure Mechanics (LaBS), Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, 20133 Milan, Italy. gloria.casaroli@polimi.it.
Tomaso VillaLaboratory of Biological Structure Mechanics (LaBS), Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, 20133 Milan, Italy. tomaso.villa@polimi.it.
Tito BassaniIRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy. tito.bassani@grupposandonato.it.
Nikolaus Berger-RoscherInstitute of Orthopedic Research and Biomechanics, Trauma Research Center Ulm (ZTF), Ulm University, D-89081 Ulm, Germany. nikolaus.berger-roscher@uni-ulm.de.
Hans-Joachim WilkeInstitute of Orthopedic Research and Biomechanics, Trauma Research Center Ulm (ZTF), Ulm University, D-89081 Ulm, Germany. hans-joachim.wilke@uni-ulm.de.
Fabio GalbuseraIRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy. fabio.galbusera@grupposandonato.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Finite element modeling has been widely used to simulate the mechanical behavior of the intervertebral disc. Previous models have been generally limited to the prediction of the disc behavior under simple loading conditions, thus neglecting its response to complex loads, which may induce its failure. The aim of this study was to generate a finite element model of the ovine lumbar intervertebral disc, in which the annulus was characterized by an anisotropic hyperelastic formulation, and to use it to define which mechanical condition was unsafe for the disc. Based on published in vitro results, numerical analyses under combined flexion, lateral bending, and axial rotation with a magnitude double that of the physiological ones were performed. The simulations showed that flexion was the most unsafe load and an axial tensile stress greater than 10 MPa can cause disc failure. The numerical model here presented can be used to predict the failure of the disc under all loading conditions, which may support indications about the degree of safety of specific motions and daily activities, such as weight lifting.

Indexed as

anisotropic hyperelasticannulus fibrosusfinite element analysisherniationintervertebral discovine model

Identifiers

PMID28772392
PMCPMC5344546

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.