Evidence map›Paper›PMID 28772194›Full record

ArticleBehaviour research and therapy2017

Perseverate or decenter? Differential effects of metacognition on the relationship between parasympathetic inflexibility and symptoms of depression in a multi-wave study.

Jonathan P Stange, Jessica L Hamilton, David M Fresco, Lauren B Alloy

Abstract read
In one paragraph

Article in Behaviour research and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Neurophysiological Markers of Regulation Success in Everyday Life in Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jonathan P StangeUniversity of Illinois at Chicago, United States. Electronic address: jstange@psych.uic.edu.
Jessica L HamiltonTemple University, United States.
David M FrescoKent State University, United States.
Lauren B AlloyTemple University, United States.
Temple College · USKent State University · USUniversity of Illinois Chicago · US

Funding

Training in the Neuroscience of Mental HealthT32MH067631 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI RASENICK, MARK M. · 2004 to 2024
$4.8M
Mindfulness-Based Stress Reduction for High Blood Pressure: A Two-Site RCTR01HL119977 · NHLBI · KENT STATE UNIVERSITY · PI FRESCO, DAVID M · 2014 to 2018
$3.8M
Risk for Adolescent Depression: Stress, Cognitive Vulnerability, & InflammationR01MH101168 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH · 2013 to 2017
$3.2M
SMART Center II Brain Behavior Connections in Self Management ScienceP30NR015326 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI MOORE, SHIRLEY M · 2014 to 2018
$2.8M
Inflexibility and Vulnerability to DepressionF31MH099761 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI STANGE, JONATHAN P · 2012 to 2014
$87k
Physiological Markers of Stress Generation and Affect Reactivity in DepressionF31MH106184 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI HAMILTON, JESSICA LEIGH · 2014 to 2015
$64k
NHLBI NIH HHS R01 HL119977NIMH NIH HHS F31 MH099761NIMH NIH HHS F31 MH106184NIMH NIH HHS R01 MH101168NIMH NIH HHS T32 MH067631NINR NIH HHS P30 NR015326
6 · The paper itself

Abstract

Depression often is characterized by inflexible autonomic and metacognitive processes that interfere with effective self-regulation. However, few studies have integrated these factors to improve the prediction of which individuals are at greatest risk for depression. Among 134 undergraduates, we evaluated whether parasympathetic inflexibility (a lack of reduction in respiratory sinus arrhythmia) in response to a sadness induction involving loss would prospectively predict symptoms of depression across four waves of follow-up over twelve weeks. Furthermore, we evaluated whether metacognitive components of perseverative cognition (PC) and decentering (identified by a principal component analysis) would moderate this relationship in opposite directions. Multilevel modeling demonstrated that the relationship between parasympathetic inflexibility and prospective symptoms of depression was exacerbated by PC, but attenuated by decentering. Furthermore, individuals with parasympathetic inflexibility, PC, and low decentering were at greatest risk for symptoms of depression across follow-up. These results support the utility of integrating autonomic and metacognitive risk factors to identify individuals at risk for depression.

Indexed as

MetacognitionDepressionFemaleHumansMaleRespiratory Sinus ArrhythmiaYoung AdultDecenteringDepressionFlexibilityRespiratory sinus arrhythmiaRisk factorsRuminationWorry

Identifiers

PMID28772194
PMCPMC5600695
OpenAlexW2735284036

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.