ArticlePloS one2017
A Genome Wide Association Study of arabinoxylan content in 2-row spring barley grain.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 50 citations in OpenAlex.
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- Morphological and developmental analysis of Plantago spp. seed capsules reveals key features of the dehiscence zones.Annals of botany · 2025Article
- Variety-dependent accumulation of glucomannan in the starchy endosperm and aleurone cell walls of rice grains and its possible genetic basis.Plant biotechnology (Tokyo, Japan) · 2023Article
- Genetic dissection of monosaccharides contents in rice whole grain using genome-wide association study.The plant genome · 2023Article
- Genome-wide association and targeted transcriptomic analyses reveal loci and candidate genes regulating preharvest sprouting in barley.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Natural variation inFrontiers in plant science · 2023Article
- Genome-Wide Association Study of Arabinoxylan Content from a 562 Hexaploid Wheat Collection.Plants (Basel, Switzerland) · 2023Article
- Arabinoxylan as well as β-glucan in barley promotes GLP-1 secretion by increasing short-chain fatty acids production.Biochemistry and biophysics reports · 2022Article
- The evolutionary patterns of barley pericentromeric chromosome regions, as shaped by linkage disequilibrium and domestication.The Plant journal : for cell and molecular biology · 2022Article
- Bioactive Compounds and Antioxidant Capacity in Pearling Fractions of Hulled, Partially Hull-Less and Hull-Less Food Barley Genotypes.Foods (Basel, Switzerland) · 2021Article
- A Genome-Wide Association Study Pinpoints Quantitative Trait Genes for Plant Height, Heading Date, Grain Quality, and Yield in Rye (Frontiers in plant science · 2021Article
- Nutritional properties of selected superfood extracts and their potential health benefits.PeerJ · 2021Article
- A Glycoside Hydrolase Family 62 A-L-Arabinofuranosidase fromFoods (Basel, Switzerland) · 2020Article
- A small-scale fractionation pipeline for rapid analysis of seed mucilage characteristics.Plant methods · 2020Article
- Overexpression of HvCslF6 in barley grain alters carbohydrate partitioning plus transfer tissue and endosperm development.Journal of experimental botany · 2020Article
- Molecular Mechanism of Functional Ingredients in Barley to Combat Human Chronic Diseases.Oxidative medicine and cellular longevity · 2020Review
- Genetic variation of HvXYN1 associated with endoxylanase activity and TAX content in barley (Hordeum vulgare L.).BMC plant biology · 2019Article
- Harnessing Novel Diversity From Landraces to Improve an Elite Barley Variety.Frontiers in plant science · 2019Article
- Differences in hydrolytic enzyme activity accompany natural variation in mature aleurone morphology in barley (Hordeum vulgare L.).Scientific reports · 2018Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In barley endosperm arabinoxylan (AX) is the second most abundant cell wall polysaccharide and in wheat it is the most abundant polysaccharide in the starchy endosperm walls of the grain. AX is one of the main contributors to grain dietary fibre content providing several health benefits including cholesterol and glucose lowering effects, and antioxidant activities. Due to its complex structural features, AX might also affect the downstream applications of barley grain in malting and brewing. Using a high pressure liquid chromatography (HPLC) method we quantified AX amounts in mature grain in 128 spring 2-row barley accessions. Amounts ranged from ~ 5.2 μg/g to ~ 9 μg/g. We used this data for a Genome Wide Association Study (GWAS) that revealed three significant quantitative trait loci (QTL) associated with grain AX levels which passed a false discovery threshold (FDR) and are located on two of the seven barley chromosomes. Regions underlying the QTLs were scanned for genes likely to be involved in AX biosynthesis or turnover, and strong candidates, including glycosyltransferases from the GT43 and GT61 families and glycoside hydrolases from the GH10 family, were identified. Phylogenetic trees of selected gene families were built based on protein translations and were used to examine the relationship of the barley candidate genes to those in other species. Our data reaffirms the roles of existing genes thought to contribute to AX content, and identifies novel QTL (and candidate genes associated with them) potentially influencing the AX content of barley grain. One potential outcome of this work is the deployment of highly associated single nucleotide polymorphisms markers in breeding programs to guide the modification of AX abundance in barley grain.
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